objective(s) extensive use of quinolones has been associated with raising level of resistance. in the current, we focused on assessing the prevalence of escherichia coli resistance to quinolones and frequency of qnra, qnrb and qnrs in non esbls (extended spectrum beta-lactamases) and esbls producing e. coli with blashv and blatem. materials and methods one hundred and fifty e. coli isolates wer...

objective(s): we investigated the contribution of gyra and parc mutational mechanism in decreased ciprofloxacin susceptibility of acinetobacter baumannii isolated from burn wound infections. materials and methods: ciprofloxacin susceptibility of 50 a. baumannii isolates was evaluated by disk diffusion and agar dilution methods. pcr and sequencing were performed for detection of mutation in gyra...

BACKGROUND Wide use of ciprofloxacin and levofloxacin has often led to increased resistance. The resistance rate to these two agents varies in different clinical isolates of Enterobacteriaceae. Mutations of GyrA within the quinolone resistance-determining regions have been found to be the main mechanism for quinolone resistance in Enterobacteriaceae. It has been shown that only some of the muta...

Sir, We report here a study that was undertaken to investigate whether ciprofloxacin resistance in Gram-negative noso-comial pathogens is a surrogate marker for cross-resistance to non-fluoroquinolones. The organisms, Escherichia coli (n = 3315), Pseudomonas aeruginosa (n = 1370), Entero-bacter aerogenes (n = 252), Enterobacter cloacae (n = 495), Proteus mirabilis (n = 379), Serratia marcescens...

OBJECTIVES The aim of this study was to update data on levofloxacin/ciprofloxacin and triple resistance (resistance to metronidazole, clarithromycin and levofloxacin/ciprofloxacin) in Helicobacter pylori clinical isolates and to identify the impact of prior eradication therapies on their development. METHODS We tested the antimicrobial susceptibility to amoxicillin, metronidazole, clarithromy...

A significant increase in the isolation frequency of ciprofloxacin-resistant Escherichia coli was observed in the haematology departments of two university hospitals in The Netherlands. Amplified fragment length polymorphism analysis revealed that this increase was not caused by the emergence of unique ciprofloxacinresistant clones. Determination of the presence of class 1 integrons indicated t...

OBJECTIVE To determine the frequency of E. coli resistance to ciprofloxacin and common factors leading to it among patients presenting with urinary tract infection. STUDY DESIGN Descriptive cross-sectional study. PLACE AND DURATION OF STUDY Department of Medicine, Ayub Teaching Hospital, Abbottabad, from December 2011 to June 2012. METHODOLOGY A total of 166 patients, > 18 years of age of...

This article presents the incidence of ciprofloxacin resistance among 480 clinical isolates obtained from patients with urinary tract infection (UTI) during January to June 2004 in Gaza Strip, Palestine. The resistance rates observed were 15.0% to ciprofloxacin, 82.5% to amoxycillin, 64.4% to cotrimoxazole, 63.1% to doxycycline, 32.5% to cephalexin, 31.9% to nalidixic acid, and 10.0% to amikaci...

BACKGROUND During the last decade the resistance rate of urinary Escherichia coli (E. coli) to fluoroquinolones such as ciprofloxacin has increased. Systematic reviews of studies investigating ciprofloxacin resistance in community- and hospital-acquired E. coli urinary tract infections (UTI) are absent. This study systematically reviewed the literature and where appropriate, meta-analysed studi...