نتایج جستجو برای: cineole

تعداد نتایج: 853  

2011
Luci Moore

Neotropical orchids of subtribes Stanhopeinae and Catasetinae are exclusively pollinated by euglossine bees (Euglossini). This study determines whether orchids present specific combinations and proportions of chemical odors in order to attract a limited subset of euglossine bee species, thereby avoiding hybridization that may result from the attraction of too many pollinators. Chemical baits of...

Journal: :Canadian journal of physiology and pharmacology 2002
Saad Lahlou André Fernandes Figueiredo Pedro Jorge Caldas Magalhães José Henrique Leal-Cardoso

The cardiovascular effects of i.v. treatment with 1,8-cineole, a monoterpenic oxide present in many plant essential oils, were investigated in normotensive rats. This study examined (i) whether the autonomic nervous system is involved in the mediation of 1,8-cineole-induced changes in mean aortic pressure (MAP) and heart rate (HR) and (ii) whether the hypotensive effects of 1,8-cineole could re...

Journal: :Xenobiotica; the fate of foreign compounds in biological systems 2007
S McLean R R Boyle S Brandon N W Davies J S Sorensen

1,8-Cineole (cineole) is a Eucalyptus leaf toxin that defends against predation by herbivores such as the brushtail possum (Trichosurus vulpecula). The aim of the current study was to characterize the pharmacokinetics of cineole in the possum to improve understanding about how possums can avoid cineole toxicity when eating a Eucalyptus diet. Nine male possums were trapped in the wild and acclim...

Journal: :Biochimica et biophysica acta 2005
Mike Duisken Frank Sandner Brunhilde Blömeke Juliane Hollender

Human metabolism of the monoterpene cyclic ether 1,8-cineole was investigated in vitro and in vivo. In vitro, the biotransformation of 1,8-cineole was investigated by human liver microsomes and by recombinant cytochrome P450 enzymes coexpressed with human CYP-reductase in Escherichia coli cells. Besides the already described metabolite 2alpha-hydroxy-1,8-cineole we found another metabolite prod...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2001
M Miyazawa M Shindo T Shimada

1,8-Cineole, the monoterpene cyclic ether known as eucalyptol, is one of the components in essential oils from Eucalyptus polybractea. We investigated the metabolism of 1,8-cineole by liver microsomes of rats and humans and by recombinant cytochrome P450 (P450 or CYP) enzymes in insect cells in which human P450 and NADPH-P450 reductase cDNAs had been introduced. 1,8-Cineole was found to be oxid...

2017
Merih Şimşek Reşat Duman

BACKGROUND Chlorhexidine belongs to a group of medicines called antiseptic antibacterial agents. Chlorhexidine is commonly used for the care and clean off the skin, hands, and wounds. In recent years, medicinal and aromatic plants have been used for prevention of disease, maintaining health, and improving disease in traditional and modern medicine as a medicament. According to recent research, ...

2017
Jangho Lee Su Jeong Ha Joon Park Yong Ho Kim Nam Hyouck Lee Young Eon Kim Yoonsook Kim Kyung-Mo Song Sung Keun Jung

1,8-cineole is a natural monoterpene cyclic ether present in Eucalyptus, and has been reported to exhibit anti-inflammatory and antioxidant effects. However, the preventive effect of 1,8-cineole on skin carcinogenesis and the molecular mechanism of action responsible remains unknown. In the present study, we investigated the effect of 1,8-cineole on UVB-induced skin carcinogenesis. 1,8-cineole ...

Journal: :Neuroscience Letters 2015
Francisco Walber Ferreira-da-Silva Kerly Shamyra da Silva-Alves Thaís Antônia Alves-Fernandes Andrelina Noronha Coelho-de-Souza José Henrique Leal-Cardoso

1,8-Cineole is a terpenoid present in many essential oil of plants with several pharmacological and biological effects, including antinociceptive, smooth muscle relaxant and ion channel activation. Also, 1,8-cineole blocked action potentials, reducing excitability of peripheral neurons. The objective of this work was to investigate effects of 1,8-cineole on Na(+) currents (INa(+)) in dissociate...

2015
Soichiro Murata Koichi Ogawa Takashi Matsuzaka Mitsuru Chiba Ken Nakayama Kenichi Iwasaki Tomohiro Kurokawa Naoki Sano Tomohito Tanoi Nobuhiro Ohkohchi Johannes Haybaeck

Hepatocyte-specific Phosphatase and tensin homolog (Pten)-knockout (KO) mice exhibit hepatic lesions analogous to non-alcoholic steatohepatitis (NASH). 1,8-cineole is a monoterpene oxide and it has several biological effects including hepatoprotective effects. In this study we revealed that 1,8-cineole ameliorates NASH of Pten KO mice. Pten KO mice were assigned to a control group without any m...

Journal: :Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2001
R Boyle S McLean W Foley N W Davies E J Peacock B Moore

The in vivo metabolic fate of 1,8-cineole was investigated in six male koalas. Koalas were fed ad lib a diet of Eucalyptus cephalocarpa leaf with a 1,8-cineole concentration of 2.53+/-0.70% dry mass of leaf, corresponding to a 1,8-cineole intake of 2.4+/-1.1 mmol/kg (3.1+/-1.3 g). Urine and faeces were collected for 24 h and metabolites identified by GC-MS and LC-MS. Metabolites were quantified...

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