نتایج جستجو برای: ciclopirox olamine

تعداد نتایج: 195  

Journal: :The Journal of antimicrobial chemotherapy 2005
Robin E B Lee Teresa T Liu Katherine S Barker Richard E Lee P David Rogers

OBJECTIVES The aim of this study was to identify changes in the gene expression profile of Candida albicans upon exposure to the hydroxypyridone anti-infective agent ciclopirox olamine in an effort to better understand its mechanism of action. METHODS C. albicans SC5314 was exposed to either medium alone or ciclopirox olamine at a concentration equivalent to the IC50 (0.24 mg/L) for 3 h. RNA ...

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Journal: :Antimicrobial agents and chemotherapy 2003
Markus Niewerth Donika Kunze Michael Seibold Martin Schaller Hans Christian Korting Bernhard Hube

The hydroxypyridone ciclopirox olamine belongs to the antimycotic drugs used for the treatment of superficial mycoses. In contrast to the azoles and other antimycotic drugs, its specific mode of action is only poorly understood. To investigate the mode of action of ciclopirox olamine on fungal viability, pathogenicity, and drug resistance, we examined the expression patterns of 47 Candida albic...

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Journal: :In vivo 2011
Young Kim Petra Alpmann Sabine Blaum-Feder Simon Krämer Tomoyuki Endo Desheng Lu Dennis Carson Ingo G H Schmidt-Wolf

BACKGROUND It was recently confirmed that the antifungal agent ciclopirox olamine inhibits Wnt/beta catenin signaling in myeloma. Piroctone olamine (PO) has very similar chemical features to ciclopirox olamine. MATERIALS AND METHODS This study investigated the antitumor effect of PO in vitro and in vivo in a murine myeloma model. RESULTS PO demonstrated a major apoptotic activity in various...

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Journal: :Analytical Sciences: X-ray Structure Analysis Online 2003

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Journal: :International journal of advanced research 2021

Onychomycosis is a common fungal infection of nail plate caused by dermatophytes, non dermatophyte molds & yeasts. Tinea unguium on the other hand refers specifically to dermatophytes. represents 50% all disorders and 30% mycotic infections skin.1 It distributed worldwide with prevalence 3% 9%. generally considered as disease middle aged elderly affecting large significant number people. Th...

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Journal: :International Journal of Dermatology 2007

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Journal: Journal of Mycology Research 2015
Alireza Farasat, Azar Sabokbar, Farideh Zaini, Mahin Safara, Mahmoud Mahmoudi, Mohammad Ali Esfandiary, Mohammad Amin Esfandiary, Mohammad Ghahri, Parivash Kordbacheh, Sanaz Abbasi, Shahram Mahmoudi,

The aim of the present study was to investigate the antifungal activity of Zatariamultiflora essential oil, fluconazole and ciclopirox olamine against 44 non-albicansCandida isolates from patients with recurrent vulvovaginal candidiasis. A set of C.glabrata (29 strains), C. krusei (3 stains) and C. patapsilosis (2 strains) were studiedusing Clinical and Laboratory Standards Institute (CLSI) bro...

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Journal: :journal of mycology research 2015
mohammad ali esfandiary shahram mahmoudi farideh zaini mahin safara mahmoud mahmoudi

the aim of the present study was to investigate the antifungal activity of zatariamultiflora essential oil, fluconazole and ciclopirox olamine against 44 non-albicanscandida isolates from patients with recurrent vulvovaginal candidiasis. a set of c.glabrata (29 strains), c. krusei (3 stains) and c. patapsilosis (2 strains) were studiedusing clinical and laboratory standards institute (clsi) bro...

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2016
P. CHOUHAN

The objective of the present study was to design and develop a microemulsion based transungual drug delivery formulation of ciclopirox olamine using colloidal carrier for treatment of onychomycosis. Capmul PG8 was selected as oil phase due to the high solubility of ciclopirox in it as compared to other oils and Cremophor EL and Transcutol P were used as surfactant and cosurfactant respectively....

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Journal: :Indian Dermatology Online Journal 2019

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