background: greater occipital never block has been shown to be an effective treatment in patients with cluster or tension type headache but there are very few studies investigating its effect in patients with chronic migraine. this study was to determine the effectiveness of greater occipital never block on headache in patients with chronic migraine. we designed an interventional before-after s...

This study has evaluated depression in patients with episodic migraine (n=98), chronic migraine without medication overuse (n=23), and chronic migraine with medication overuse (n=57). The Beck Depression Inventory (BDI) was used to evaluate depressive symptoms in these three groups. The mean BDI score obtained in all patients was higher than that observed in asymptomatic subjects (episodic migr...

BACKGROUND People who have a disease often experience stigma, a socially and culturally embedded process through which individuals experience stereotyping, devaluation, and discrimination. Stigma has great impact on quality of life, behavior, and life chances. We do not know whether or not migraine is stigmatizing. METHODS We studied 123 episodic migraine patients, 123 chronic migraine patien...

Migraine frequency is divided into episodic and chronic.2 Episodic migraine is characterized by <15 migraine days and chronic migraine by ≥15 headache days per month. Sometimes migraine may be described as chronic simply because the attacks recur over long periods of time. Chronic migraine affects 1.4 to 2.2 percent of adults.9 All migraine types significantly affect the physical, psychological...

Abstract Background Although migraine phenotype has been widely described, the explanation of pathophysiology still a gap that might be partly bridged by neuroimaging investigations. The aim study is to assess volumetric brain changes in migraineurs compared with controls, and episodic comparison chronic type. Structural (with without aura) were assessed an automated segmentation method (Free S...

Chronic migraine is a disabling neurologic condition that affects 2% of the general population. Patients with chronic migraine have headaches on at least 15 days a month, with at least eight days a month on which their headaches and associated symptoms meet diagnostic criteria for migraine. Chronic migraine places an enormous burden on patients owing to frequent headaches; hypersensitivity to v...

BACKGROUND Chronic migraine is a common, highly disabling, underdiagnosed and undertreated entity of migraine. It affects 0.9%-2.2% of the general adult population. The present paper overviews the preclinical and clinical data regarding the therapeutic effect of onabotulinumtoxinA in chronic migraineurs. METHODS A literature search was conducted in the database of PubMed up to 20 May 2015 for...

Background Chronic migraine is common but there is limited knowledge on associated comorbidities. Objectives To examine mental and physical comorbidities in chronic migraine and the influence of socioeconomic status in a large, nationally representative dataset. Design Analysis of cross-sectional primary healthcare data from 1,468,404 adults in Scotland. Chronic migraine, 31 other physical ...

Migraine is a neurovascular disorder that is characterized by unilateral, pulsatile headaches. Migraine due to its individual and social effects is known as a major cause of disability in the world. The main complication of this disease is chronification that is known as chronic migraine (CM). It seems that several factors contribute to migraine chronification such as age, female gender, obesit...

Chronic migraine is a debilitating neurobiological disorder that affects approximately 1.4-2.2% of the population worldwide. Patients with chronic migraine have 15 or more headache days per month, with at least 8 days per month that meet the criteria for migraine. Injection of onabotulinumtoxinA, using a standardized injection protocol, was approved by the US Food and Drug Administration in 201...