a novel type of brainstem-predominant encephalomyelitis was first described as chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (clippers) in 2010 by pittocket al and then few additional patients were reported. here we report a 50-year-old iranian male who presented with a number of clinical features described as typical for clippers. the association...

INTRODUCTION Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids is a brainstem disorder characterized by perivascular pathologic reaction with lymphocyte infiltration and leading to diplopia, facial palsy, dysarthria, and gait ataxia. It was thought to be an autoimmune disorder without distinct pathogenesis. Chronic hepatitis B virus infection has been...

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a newly named condition of pontine-centric inflammatory disorder. 1) The cardinal feature of the disease is punctate gadolinium enhancement " peppering " the pons on magnetic resonance imaging (MRI). The unique MRI features

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a brainstem relapsing-remitting inflammatory disease. To date, no treatment besides corticosteroids has been shown to be effective to treat relapses. We report a patient with CLIPPERS initially misdiagnosed with CNS tuberculosis who presented with brainstem attacks responsive to antituber...

Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) syndrome is a rare neurological disorder uncertain etiology, pathogenesis and clinical course. Pittock et al. in 2010 first described this chronic inflammatory neurologic condition, which preferably affects the brainstem. There an infiltration cells of affected regions typical dotted curvili...

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) syndrome is a clinically and radiologically distinct pontine-predominant perivascular neuroinflammation showing T lymphocyte infiltration. It is assumed to have an autoimmune or other inflammatory mediated pathogenesis. We report the first known case of CLIPPERS in East Asia, characterized b...