conclusions the apri had the highest sensitivity and specificity (64% and 71%, respectively) for prediction of the presence of liver disease. we suggest that apri may be applicable for the detection of a severe liver disease. objectives in this study, we evaluated and compared several available indices of the severity of liver diseases in patients with hepatitis. patients and methods exclusion ...

introduction worldwide, chronic liver disease is a major cause of morbidity and mortality. causes of elevated serum alanine aminotransferase (alt) levels vary depending on the population under study. the aim of this study is to evaluate the frequency and causes of persistently elevated alt levels in patients of the gastroenterology (gi) clinics in ghaem and emam reza hospitals in mashhad, iran....

background: hepatitis e virus is an enterically transmitted virus that is endemic in south asia and this virus is one of the most important cause of acute hepatitis in this region. although hepatitis e virus (hev) is not a leading cause for chronic hepatitis, the role of hev in exacerbation of chronic liver disease is certain. materials and methods: 100 cirrhotic cases (50 hepatitis b and 50 he...

chronic liver diseases in children is the result of many different diseases including: metabolic, genetic, infectious, toxic and idiopathic causes. this was a case series study on 133 infants and children with age range 6 month to 12 years old, who presented clinically with manifestation of chronic liver disease and were admitted to children hospital medical center from year 1999 to 2000. in th...

ramadan is a sacred month for muslims all around the world. during this lunar-based month, healthy adult muslims are obligated to abstain from eating, drinking, smoking, or using oral medications from predawn to sunset. followers will typically eat just after sunset and again before dawn (1). the islamic lunar hijri calendar is 11 days shorter than the gregorian solar calendar, and therefore, t...

background vitamin d deficiency is believed to cause variety of abnormalities such as liver stiffness and fibrosis. it is also shown that vitamin d deficiency may result in chronic liver disease or liver cirrhosis. in this study, we aimed to systematically review the literature wherein the relationship between vitamin d deficiency and the severity of chronic liver disease or liver cirrhosis had...

The liver is involved in the synthesis and metabolism of many kinds of hormones, various abnormalities hormone levels are found in advanced liver disease. For example the liver is, extremely sensitive to changes in insulin or glucagon levels. The liver is the primary organ of iron storage is frequently involved, diabetes is common in patients with iron overload and may be seen in cirrhosis. Chr...

the liver is involved in the synthesis and metabolism of many kinds of hormones, various abnormalities hormone levels are found in advanced liver disease. for example the liver is, extremely sensitive to changes in insulin or glucagon levels. the liver is the primary organ of iron storage is frequently involved, diabetes is common in patients with iron overload and may be seen in cirrhosis. chr...

results bw was lower for the 5/6 nx group rats after the operations compared with the bw of those in the sham operation group. furthermore, the 5/6 nx group showed elevations in blood pressure, cr, bun, alt, and ast levels compared with the sham group over the course of time. conclusions in summary, ckd induced by the 5/6 nx model caused hypertension and increased serum levels of cr, bun, alt, ...

introduction: chronic liver disease and cirrhosis are the most important causes of growth failure, morbidity and mortality in children. cirrhosis consists of a variety of congenital, genetic, metabolic, and infectious causes in children. models for predicting of chronic liver disease severity, survival, and transplantation are useful for decision-making as well as medical interventions. the mos...