Abstract Leishmaniasis is a protozoal infection transmitted by sandfly vector; there are three main types of leishmaniasis: cutaneous leishmaniasis (CL), mucocutaneous (MCL), and visceral (VL). Herein, we present case endonasal in 34-year-old Yemeni patient who presented with disfiguring nasal swelling associated fever, swab from the lesion direct microscopic examination proved to have leishman...

Leishmaniasis is a common parasitic disease classified to acute and chronic types based on the duration of the disease. The acute lesion is presented as ulcerated papule and nodule that heal after a few months with an atrophic scar. The chronic form of cutaneous leishmaniasis is a nonhealing lesion that is persistent for more than one year. Here, we describe a chronic case of leishmaniasis deve...

Background: Chronic lupoid leishmaniasis (CLL) is a chronicform of cutaneous leishmaniasis that is usually resistant to antileishmania agents and leishmania is not seen in the histologicsections. We used polymerase chain reaction (PCR) to detectleishmania DNA in CLL specimens.Method: This descriptive cross sectional study was done on20 paraffin embedded specimens of CLL cases referred to theder...

Background & Aims: Dry type localized cutaneous Leishmaniasis due to Leishmania tropica is one of the most prevalent cutaneous parasitic infections in Kerman province. It seems that cellular immune response and the nature of immune inflammatory cells comprising the inflammatory background play a determinant role in this infection. Methods: Skin biopsies of 53 patients with acute(<2 years durati...

the aim of this study was to measure the alterations in serum zinc (zn) copper (cu) and iron (fe) concentrations in patients with acute and chronic cutaneous leishmaniasis. serum zinc and copper were measured by flameless atomic absorption spectrophotometer and serum iron concentration was measured by the ferrozine method with commercial kits and assay was carried out by using an automatic anal...

Leishmaniasis is a chronic, vector-borne parasitic disease caused by flagellated protozoan of the genus Leishmania, which has more than 20 species. Usually, it that affects tropical and subtropical populations world. The transmitted through bite female mosquitoes Lutzomyiaen Phlebotomusen. clinical presentation its manifestations are variable, they affected species immunological state host. Gen...

Background: It appears that chronic lupoid leishmaniasis is the result of type 2 predominant T helper response to parasite and a defect in the down regulation of IL-4 production during infection. The objective of this study was to evaluate the underlying immune status in these patients and their predominant T helper activity we considered serum IgE as an indicator of TH2 activity and IL-4...

Leishmaniasis, an infectious disease endemic in tropical, Asian and southern European countries, is caused by obligate intramacrophage protozoa and is transmitted through the bite of infected female sandflies. More than 20 leishmanial species are responsible for four main clinical syndromes: cutaneous leishmaniasis; mucocutaneous leishmaniasis; visceral leishmaniasis, also known as kala-azar, a...