objective: chronic infection of hepatitis b and hepatitis c are considered as the most important infectious diseases, which lead to drastic consequences such as liver dysfunction. depression is a psychiatric disorder which is concomitantly present in these patients, and decreases the patients’ quality of life. it may lead to suicide, homicide or intentional transmission of infectious to others....

context the pnpla3 i148m variant has been recognized as a genetic determinant of liver fat content and a genetic risk factor of liver damage progression associated with steatohepatitis. the i148m variant is associated with many chronic liver diseases. however, its potential association with inflammatory and autoimmune liver diseases has not been established. evidence acquisition we systemically...

Nowadays viral hepatitis is one of the most common and important causes of chronic liver disorders in the world. Extrahepatic manifestations of viral hepatitis consist a main part of the disease. The main viruses causing hepatitis include Hepatitis A, B and C viruses. Herein common skin manifestations in hepatitis C virus (HCV) are discussed. Chronic hepatitis causes skin disorders both directl...

results the mean age of chb patients was 38.5± 11.9 years and 55.9% of them (231 patients) were male. there were 13 cases (3.1%) with hdv infection. there was no association between positive anti-hdv serology and factors such as age, gender, carrier state, liver enzymes, and positive hepatitis b e antigen (hbeag) serology. conclusions although hdv had a low prevalence in our area, it is importa...

background occult hepatitis b virus infection (obi) is defined as the presence of hepatitis b virus (hbv) dna in the liver and/or in the serum of patients with negative results of hepatitis b s antigen (hbsag) test with or without serological markers of previous viral exposure. the impact of obi in patients with chronic hepatitis c (chc) is still unclear. objectives the aim of this study was to...

    Abstract   Background: Hepatitis B virus infection is an important cause of liver morbidity and   mortality worldwide. HDV changes the natural course of HBV. The prevalence of HDV infection wasn’t determined in the various groups of HBV infection (carriers, acute hepatitis, chronic hepatitis, cirrhosis and HCC) in Iran. We aimed to research the prevalence of hepatitis D virus infection in v...

â  â  hepatocellular carcinoma (hcc) is a major worldwide public health concern. despite recent advances, there has been little success in improving the survival of hcc patients. due to advances in diagnostic modalities and the increasing incidence of chronic viral hepatitis and nonalcoholic fatty liver disease (nafld), both of which are well known risk factors of hcc, the prevalence of hcc is ...

در سالهای اخیر پیشرفتهای چشمگیری در تشخیص و درمان هپاتیت مزمن ب به دست آمده  و هر چند سال یک بار تغییر و تحولات قابل توجهی در نحوه درمان چنین بیمارانی به دنبال داشته است. اگرچه در چند سال اخیر راهنماهای درمانی متعددی برای هپاتیت مزمن ب در سطح دنیا ارائه شده است(5-1)، با گذشت زمان و انجام تحقیقات جدید، تفاوتهایی بین راهنماهای درمان قابل مشاهده می شود. علاوه بر این بسیاری از داروهای جدید قیمت بسی...

conclusions we introduced an anti-hbsp antibodies elisa, designed for locally circulating hbv strains. correlation observed of anti-hbsp with liver fibrosis staging regardless of viral replication and liver inflammation suggests anti-hbsp antibodies as possible indicator for hbv-associated liver fibrosis. results seven out of eighty (9%) chb patients were positive for anti-hbsp antibodies. mean...