نتایج جستجو برای: chronic hbv
تعداد نتایج: 505812 فیلتر نتایج به سال:
mutations in the human hepatitis b virus (hbv) genome contribute to its escape from host immune surveillance and result in persistent infections. the aim of this study was to characterize the molecular variations of the surface gene and protein in chronically-infected patients from the southern part of iran. the surface genes from 12 hbv chronic carriers were amplified, sequenced and ...
background and aims: the aim of this study was to determine the correlation between the hepatitis b virus surface ag (hbsag) genotypes and variations in the clinical/serological pictures among hbsag positive chronic patients from south khorasan province of iran. methods: twenty-five patients were enrolled in this study. the hbs ag gene was amplified and was directly sequenced. genotypes and nuc...
â background: hepatitis b is still a major health problem in many parts of the world. in some developing countries the most common cause of chronic hepatitis and liver cirrhosis is hepatitis b virus (hbv). the progression of chronic hepatitis b to cirrhosis andâ hepatocellular carcinoma (hcc) include such viral factors as genotype c and high levels of serum hbv dna in addition to host factors ...
background: ccr5 is a receptor for ccl3 (mip-1 α), ccl4 (mip-1 α) and ccl5 (regulated on activation normal t cell expressed and secreted (rantes)) and play important roles in recruitment of nk cells to the hbv infected liver. objectives: the main purpose of this study was to investigate the expression levels of ccr5 on the nk cells and also serum levels of rantes in chronic hbv infected (chi) p...
Background and Objectives: Hepatitis B virus (HBV) infection is a major public health problem worldwide. Islamic Republic of Iran is located in mesoendemic region (prevalence 2%-7%). The aim of this study was to assess prevalence of chronic HBV in Iran according to demographic characteristics. Methods: Medline, Embase, Science Citation Index Expanded, Ovid, Google Scholar, IranMedex, SID, Ma...
The gut microbiota in the hepatitis B virus related acute-on-chronic liver failure (HBV-ACLF) is poorly defined. We aim to uncover characteristics of HBV-ACLF and other HBV associated pathologies. analyzed microbiome patients with or pathologies healthy individuals by 16S rRNA sequencing metagenomic fecal samples. 212 HBV-ACLF, 252 chronic (CHB), 162 HBV-associated cirrhosis (HBV-LC) 877 were r...
conclusions genotype d was the main genotype detected in romanian patients with chronic hbv infection. genotype d presented both bcp and pc mutations more frequently. results we detected two hbv genotypes; a (8.1%) and d (60.5%), and a mixture of genotypes a and d (31.4%) (p < 0.001). basal core promoter (bcp) a1762t/g1764a and precore (pc) g1896a mutations were detected in these romanian patie...
conclusions the results indicated that there was a positive association between susceptibility to chronic hbv infection and tnf-α polymorphism. in addition, hbv patients carrying -308 gg, -857 cc, and -863 aa genotypes with lower serum levels of tnf-α had an increased risk of infection. background the host genetic background regulates the natural history of chronic hepatitis b virus (hbv) infec...
Background: To determine the possible sources for the transmission of Hepatitis B Virus (HBV) infection to children in Babol, North of Iran.Methods: Forty-five boys and 35 girls with the mean age of 9.2±5.1 years were evaluated from 1993 to 2004. Hepatitis B viral markers in all the family members were assessed. The risk factors for other sources were also determined.Results: Sixty-five (81.3%)...
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