Depression occurs frequently in patients with diabetes mellitus. Chromium picolinate, an essential trace element is recommended for diabetes and also has been reported to benefit depression, but its mechanism is still debated. To investigate the mechanism, we studied its effects on serum insulin, serum glucose and on modified forced swimming test, a behavioural paradigm for depression in rats. ...

Our previous study showed that chromium malate improved the regulation of blood glucose in mice with alloxan-induced diabetes. The present study was designed to evaluate the effect of chromium malate on glycometabolism, glycometabolism-related enzymes and lipid metabolism in type 2 diabetic rats. Our results showed that fasting blood glucose, serum insulin level, insulin resistance index and C-...

AIMS/INTRODUCTION The present study was designed to evaluate the effect of chromium malate on glycometabolism, glycometabolism-related enzyme levels and lipid metabolism in type 2 diabetic rats, and dose-response and curative effects. MATERIALS AND METHODS The model of type 2 diabetes rats was developed, and daily treatment with chromium malate was given for 4 weeks. A rat enzyme-linked immun...

Background: To compare the chromium picolinate with metformin in Clomiphene citrate resistant PCOS patients. Materials and Methods: This was a randomized clinical trial being performed at university affiliated clinics including 92 women with Clomiphene citrate-resistant PCOS who were randomly assigned to receive chromium picolinate (200 μg daily) or metformin (1500 mg daily) for 3 months. Anthr...

BACKGROUND Chromium picolinate could be effective in clomiphen citrate resistant PCOS patients. OBJECTIVE To compare the effects of chromium picolinate vs. metformin in clomiphen citrate resistant PCOS patients. MATERIALS AND METHODS The present randomized clinical trial was performed on 92 women with clomiphen citrate-resistant PCOS at the clinics which were affiliated to Shiraz University...

background: chromium picolinate could be effective in clomiphen citrate resistant pcos patients. objective: to compare the effects of chromium picolinate vs. metformin in clomiphen citrate resistant pcos patients. materials and methods: the present randomized clinical trial was performed on 92 women with clomiphen citrate-resistant pcos at the clinics which were affiliated to shiraz university ...

In some studies in diabetic people, chromium picolinate supplementation has lowered readings for both plasma triglycerides and blood sugar. In the present study, relatively low dose supplementation (200 μg chromium) did not lower blood sugar readings, but did lower triglyceride values in people with the following characteristics: type 2 diabetes, moderately elevated blood sugar, and not using i...

This paper addresses the potential economic benefits of chromium picolinate plus biotin (Diachrome) use in people with Type 2 diabetes (T2DM). The economic model was developed to estimate the impact on health care systems' costs by improved HbA1C levels with chromium picolinate plus biotin (Diachrome). Lifetimes cost savings were estimated by adjusting a benchmark from the literature, using a p...

objective: type 2 diabetes mellitus is a complex metabolic disorder with adverse cardiovascular risk. chromium (cr) is an essential nutrient and its role in carbohydrate and lipid metabolism has not been clarified especially in iran. the aim of this study was to evaluate the effect of chromium picolinate administration on blood glucose, hba1c, lipid profile and lipid peroxidation in type 2 diab...