leiomyoma is a very rare intraocular tumor, which can occur in the iris, ciliary body and choroids. we report a case of choroidal leiomyoma in a 16-years old women whose left eye was enucleated because of clinical suspicion for melanoma. using conventional light microscopy tumor was interpreted as spindle cell tumor, most probably of neurogenic origin and after using immunohistochemical studies...

Choroidal osteoma is a rare intraocular bony tumor that typically manifests as a yellow-white, well-demarcated mass with geographic pseudopodal margins.1-3 This benign tumor predominantly occurs in the peripapillary or papillomacular region, most often in young women.1,2 Occasionally, choroidal osteoma can simulate an amelanotic choroidal tumor such as melanoma, nevus, or metastasis.1,2 This tu...

Choroidal osteoma is a unique tumor that comprises mature bone in the circumpapillary or macular region.1 Choroidal osteoma showed evolution with change in clinical features over many years, and cases of tumor growth, tumor decalcification or involution, and related choroidal neovascularization (CNV) were documented.1-4 Herein, we present a case of choroidal osteoma with serous retinal detachme...

We report a case of metastatic choroidal carcinoid tumor with favorable outcome after photodynamic therapy. A 75-year-old woman was presumptively diagnosed with bilateral choroidal metastases from carcinoid tumor. Although the tumor in the right eye showed a tendency toward rapid expansion and required aggressive treatment to preserve vision, the size was still small and we hesitated to use ext...

Purpose. To report a case of atypical dome-shaped choroidal osteoma, which was diagnosed by histopathological finding of surgically extracted tumor. Case Report. A 35-year-old woman presented with visual field abnormality in the left eye (OS). Her best-corrected visual acuity with Landolt ring chart was 1.0 OS. The funduscopic examination revealed a yellowish dome-shaped choroidal tumor located...

OBJECTIVE To evaluate choroidal osteoma for tumor growth, tumor decalcification, related choroidal neovascularization, visual acuity loss, and poor visual acuity. DESIGN Retrospective nonrandomized single-center case series. SETTING Ocular Oncology Service at Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pa. PARTICIPANTS There were 74 eyes of 61 patients with choroidal os...

Purpose To demonstrate the clinical pathologic correlation in a hemorrhagic choroidal melanoma. Observations A 52 year old patient presented with a large choroidal mass associated with vitreous and retinal hemorrhage. The eye was enucleated and histopathology demonstrated epithelioid-type MART1 positive tumor cells consistent with choroidal melanoma. The tumor had broken through Bruch's membr...

PURPOSE To compare estrogen (ER), progesterone (PR), and human epidermal growth factor-2 (HER2) receptor expression in the primary tumor of patients affected by choroidal metastases from breast carcinoma (BC) versus those with extraocular metastases. METHODS Eighteen consecutive patients affected by choroidal metastases from BC were included. We defined ER, PR, and HER2 positivity of the prim...

PURPOSE To report the clinical and paraclinical features of two patients with orange- colored choroidal metastases in whom the primary cancers have not previously been associated with such lesions. CASE REPORT Orange-colored choroidal lesions were detected on the fundus examination of one patient with metastatic small cell neuroendocrine tumor of the larynx and oropharynx, and in another subj...

CHOROIDAL NEVUS Choroidal nevus (Figure 1), the most common primary intraocular tumor,1 is a benign tumor that arises from melanocytic cells derived from the neural crest. Choroidal nevi are more common in white people, with 4% of the population having at least one.1 Malignant transformation into melanoma is possible; therefore, choroidal nevi should be monitored even though the rate is 1 in 4,...