choroid plexus papillomas are rare intracranial tumors, accounting for less than 1% of all intracranial tumors in adults. however, they are relatively more common in children and constitute 1.5 to 4% of childhood intracranial tumors. in children, choroid plexus papillomas are predominately located in the lateral ventricles, followed by the forth and third ventricles and, rarely, in the cerebell...

BACKGROUND The Wnt and BMP signaling pathways are involved in the morphogenesis of both gastrointestinal and choroid plexus epithelium. In the intestine, Wnt signaling represses the expression of the tumor suppressor gene CDX2 via SOX9, a transcription factor, which is also expressed in the choroid plexus. Recently, an inverse correlation between CDX2 expression and tumor grade, tumor stage and...

[n diagnostic iieuropathology, the histological distinctions betweeii nonn"l choroid plexus, typical aiid atypical choroid plexus papilloma aiid choroid plexus carciiioma may cause difficulties. [mmunohistocheinistry was applied for proliferatiiig cell nuclear antigeii oii 7 samples of nonnal choroid plexus, 12 typical papillomas, 10 atypical papillomas, and 3 choroid plexus carcinomas to evalu...

The choroid plexus, an epithelial-based structure localized in the brain ventricle, is the major component of the blood-cerebrospinal fluid barrier. The choroid plexus produces the cerebrospinal fluid and regulates the components of the cerebrospinal fluid. Abnormal choroid plexus function is associated with neurodegenerative diseases, tumor formation in the choroid plexus epithelium, and hydro...

OBJECT Malignant progression of choroid plexus papillomas has been occasionally reported, but this issue has not yet been systematically addressed. METHODS Frequency and extent of malignant progression were examined in a retrospective series of 124 primary choroid plexus papillomas using uniform histological criteria. RESULTS After gross-total resection and a mean follow-up period of 59 mon...

The choroid plexus produces cerebrospinal fluid and plays an important role in brain homeostasis both pre and postnatally. In vitro studies have suggested that cells from adult choroid plexus have stem/progenitor cell-like properties. Our initial aim was to investigate whether such a cell population is present in vivo during development of the choroid plexus, focusing mainly on the chick choroi...