purpose : to introduce a novel classification system for the extent of choroid invasion and to analyze the incidence of histopathologic risk factors (hrfs) in the patients with retinoblastoma in china methods : the clinical data of 104 enucleated eyes diagnosed with retinoblastoma were retrospectively reviewed, and the pathological re-examination of the enucleated eyes was conducted. results : ...

choroid plexus papillomas are rare intracranial tumors, accounting for less than 1% of all intracranial tumors in adults. however, they are relatively more common in children and constitute 1.5 to 4% of childhood intracranial tumors. in children, choroid plexus papillomas are predominately located in the lateral ventricles, followed by the forth and third ventricles and, rarely, in the cerebell...

[n diagnostic iieuropathology, the histological distinctions betweeii nonn"l choroid plexus, typical aiid atypical choroid plexus papilloma aiid choroid plexus carciiioma may cause difficulties. [mmunohistocheinistry was applied for proliferatiiig cell nuclear antigeii oii 7 samples of nonnal choroid plexus, 12 typical papillomas, 10 atypical papillomas, and 3 choroid plexus carcinomas to evalu...

BACKGROUND The Wnt and BMP signaling pathways are involved in the morphogenesis of both gastrointestinal and choroid plexus epithelium. In the intestine, Wnt signaling represses the expression of the tumor suppressor gene CDX2 via SOX9, a transcription factor, which is also expressed in the choroid plexus. Recently, an inverse correlation between CDX2 expression and tumor grade, tumor stage and...

The choroid plexus, an epithelial-based structure localized in the brain ventricle, is the major component of the blood-cerebrospinal fluid barrier. The choroid plexus produces the cerebrospinal fluid and regulates the components of the cerebrospinal fluid. Abnormal choroid plexus function is associated with neurodegenerative diseases, tumor formation in the choroid plexus epithelium, and hydro...

Introduction Choroid plexus tumors (CPT) are defined as papillary neoplasms originating from the epithelium of the choroid plexus within the ventricles. They are classified into mainly two types: -benign choroid plexus papillomas (CPP) (World Health Organization WHO grade I) and -choroid plexus carcinomas (WHO grade III). [1,3] An intermediate group lies between the two groups and is referred t...