with significant improve in health-care and treatment of infectious diseases, genetic disorders have created a new era of notification. changes in social attitude towards family life and tendency of parents for limited number of children, sense of responsibility of parents for mental and physical healthiness of children along with their education, needed a new strategy. since most genetic disor...

Reprint request: Dr. M.L. Kulkarni, Professor of Pediatrics, 2373, MCC A Block, Davangere 577 004. methods of obtaining fetal tissues for karyotype, DISFA studies and enzyme assay(4). The procedure is done at 8-11 weeks of gestation. The transcervical sampling involves insertion of various types of catheters transcervically under ultrasound guidance for aspiration of chorionic villi. Transabdom...

There have been many diagnostic techniques using amniotic fluid or placental villi, for which needed puncture of amniotic fluid (amniocentesis) and placental villi sampling (CVS) in early pregnancy. The techniques accompany some risk factors of fetal demise or miscarriage. Also immature fetal lung was diagnosed in preterm births by the chemical or physical property of amniotic fluid obtained by...

BACKGROUND The use of invasive devices and broad spectrum antibiotics has increased the rate of candidal superinfections. Candida sepsis associated with pregnancy is rare. Candida sepsis following chorionic villi sampling (CVS) has never been reported. CASE A 31 -year-old pregnant woman presented with signs of sepsis one day after undergoing transcervical CVS. Blood culture and curettage mate...

chorionic villus sampling (cvs) is a new method and its true risk of fetal loss and complications is not still clearly determined. the objective of this study was to review the clinical pregnancy outcome of transabdominal cvs (ta-cvs) performed on women with minor beta thalassemia. ta-cvs performed on 300 women with a singleton pregnancy and we could follow 213 women until delivery. data regard...

Chromosomal anomalies remain the commonest cause of mental retardation and congenital malformation. Traditionally, the prenatal diagnosis of chromosomal aberration relies on cytogenetic analysis of the cells obtained from amniocentesis or chorionic villus sampling (CVS). First, the amniotic fluid or chorionic villi samples need to be cultured for 14 days or more before adequate foetal cells can...

Prenatal diagnosis with application of the Amniotic fluid (Amniocentesis: AC) and chorionic villi sampling {CVS) is a general aspect of application in Human Genetics which facilitate the diagnosis of different Genetic defects, enclosing chromosomal abnormalities and Genosomopathies. Diagnosis of Genetic defects for AC and CVS is between 16-20th and 8-12th weeks of gestation respectively. Allica...

OBJECTIVE The technique used to perform transabdominal chorionic villus sampling (CVS) is not standardized, but aspiration of villi is generally obtained by discontinuous vacuum created in a syringe, manually or by a hand-grip device. We evaluated the feasibility of a new method of performing CVS which employs a 4-mL Vacutainer connected to the needle, producing a continuous negative pressure. ...