Lesch-Nyhan syndrome (LNS) is an inborn error of metabolism. Choreoathetosis, mental retardation and self-harming are the three symptoms. A genetic test that analyses gene encoding hypoxanthine-guanine phosphoribosyltransferase (HPRT) blood tests showing hyperuricaemia support diagnosis. However, relevance these results to clinical symptoms unclear. 25 years-old man consulted our hospital for s...

Both thyrotoxic periodic paralysis (TPP) and choreoathetosis are unusual complications of childhood thyrotoxicosis. We hereby report a boy who presented with both TPP and choreoathetosis at the initial presentation of his Graves disease. A 14 year-old Thai boy presented with acute generalized proximal muscle weakness and myalgia for 5 hours. Detailed history revealed the increased appetite, hea...

Paroxysmal kinesigenic choreoathetosis is an unusual movement disorder often triggered by attempts to use the limbs, and has sometimes been associated with diffuse or focal brain injury. We report its occurrence in hyperthyroidism, with which choreoathetosis has rarely been described in the past without known cause. Choreoathetosis has also occurred with other metabolic and toxic disorders, and...

Three cases of paroxysmal kinesigenic choreoathetosis are described in whom unilateral attacks were focally induced, together with a case in whom bilateral attacks only occured. Treatment with phenytoin was effective in all cases. The aspects of the literature relating to focal and generalised attacks in paroxysmal kinesigenic choreoathetosis are reviewed.

Idiopathic hypoparathyroidism presenting as convulsions along with choreoathetosis simultaneously is a distinctly rare scenario. We present a case of Idiopathic hypoparathyroidism who presented with status epilepticus along with extrapyramidal dysfunction in the form of choreoathetosis. Clinical diagnosis was confirmed by the demonstration of basal ganglia calcification in Non Contrast Computed...