the crude methanolic extract of the seeds of celastrus paniculatus along with its organic soluble fractions were tested for their possible antioxidant and anti-alzheirmer (ad) activity. the extracts showed prominent dpph free radical scavenging activity, inhibiting activity of authentic peroxynitrite (onoo-) and inhibition of total reactive oxygen species (ros) generation. in dpph radical scave...

INTRODUCTION Celastrus paniculatus seed oil, commonly known as Malkangni or Jyotishmati, was in use from time immemorial to treat brain related disorders. Celastrus paniculatus seed oil has significant antidepressant-like activity in chronic unpredictable stressed mice. The present study was undertaken to evaluate the antidepressant-like effect of Celastrus paniculatus seed oil in unstressed mi...

        The crude methanolic extract of the seeds of Celastrus paniculatus along with its organic soluble fractions were tested for their possible antioxidant and anti-alzheirmer (AD) activity. The extracts showed prominent DPPH free radical scavenging activity, inhibiting activity of authentic peroxynitrite (ONOO-) and inhibition of total reactive oxygen species (ROS) generation. In D...

Twente Uhiversity of Technology, Enschede, The Netherlands and D.D. Nanavati"and Sukh Dev National Chemical Laboratory, Poona, India (Received in 1K 25 January 1973; accepted for publication 1 Wbruary 1973) In connection with pharmacological properties ascribed to the seeds of Celastrus paniculatus Willd. (Hindi: Malkanguni), a plant mentioned in old Indian medical literature, the composition o...

Introduction: Celastrus paniculatus seed oil, commonly known as Malkangni or Jyotishmati, was in use from time immemorial to treat brain related disorders. Celastrus paniculatus seed oil has significant antidepressant-like activity in chronic unpredictable stressed mice. The present study was undertaken to evaluate the antidepressant-like effect of Celastrus paniculatus seed oil ...

introduction: celastrus paniculatus seed oil, commonly known as malkangni or jyotishmati, was in use from time immemorial to treat brain related disorders. celastrus paniculatus seed oil has significant antidepressant-like activity in chronic unpredictable stressed mice. the present study was undertaken to evaluate the antidepressant-like effect of celastrus paniculatus seed oil in unstressed m...

BACKGROUND In Indian traditional system of medicine Celastrus paniculatus extract has been used to improve intellect, memory and for the treatment of various mental disorders. PURPOSE The present study was undertaken to evaluate the effectiveness of this medicinal plant on serum biochemistry. METHODS Ethanolic extract of seed of Celastrus paniculatus (2g/kg/body weight) was orally administr...

Celastrus paniculatus is an Indian medicinal plant which has been used for thousands of years in the traditional Ayurvedic system of medicine. It is fast gaining importance in the primary healthcare systems as well as in herbal drug formulations. Oil obtained from the seeds of the plant is reported to be highly beneficial in stimulating intellect and sharpening the memory. It also acts as a pot...

Purpose: Cognitive deficit is one of the common comorbidity accompanying epilepsy. The present study evaluated the effect of Celastrus paniculatus (C- paniculatus) seed extract on seizure severity and cognitive deficit following Pentylenetetrazole (PTZ) -induced chemical kindling model. Methods: PTZ kindling model was developed by daily administration of sub-convulsive dose of PTZ 30 mg/kg for...

Soluble epoxide hydrolase inhibitors have been reported as antihypertensive, anti-inflammatory, antiulcer and anticancer actions protect the brain, heart kidney from damage. Exploring soluble inhibition activity of traditional medicinal plants helps to uncover new target treat various complications associated with inflammatory mediators. The present study was planned explore fifty commonly used...