objective: much attention is paid to angiogenesis due to its mutual role in health and disease. therefore, the effect of various chemical and physical agents on inhibition of this process has been recently studied. this study was conducted to investigate the synergic effect of glycyrrhizic acid and electromagnetic field on angiogenesis. materials and methods: in this experimental study, 44 ross...

The P1.HTR cell line includes highly transfectable cells derived from P815 mastocytoma cells originating from mouse breast tissue. Despite its widespread use in immunogenic studies, no data are available about the behavior of P1.HTR cells in the chick embryo chorioallantoic membrane model. The objective of the present investigation was to study the effects of P1.HTR cells implanted on the chori...

An assay capable of recovering individual viable rodent cells localized in various organs of the chick embryo is described. This assay is based on the differential sensitivity of chick and rodent cells to the cytotoxic drug ouabain. Utilizing this assay, the potential of the chick embryo as a model system for studying metastasis was examined. Several cell lines were characterized in three ways:...

The blood-brain barrier is characterized by still poorly understood barrier and transport functions performed by specialized endothelial cells. Hybridoma technology has been used to identify a protein termed neurothelin that is specific for these endothelial cells. Neurothelin is defined by the species-specific mouse mAb lW5 raised against lentil-lectin-binding proteins of neural tissue from em...