Protein-protein interactions play essential roles in protein function implementation. A computational model is introduced in this work for predicting protein interface residues based on amino acid chemicophysical properties only. 17 amino acid properties are selected from AAindex database and used as input features of a prediction model which is constructed by support vector machines method to ...

OBJECTIVE To determine the dental hazards associated with sports supplement drinks by investigating the chemicophysical properties of eight brands of sports drinks. METHODS The pH and titratable acidity against 0.1 M NaOH was measured. Calcium, phosphate, and fluoride concentrations and viscosities of Carbolode, Gatorade, High Five, Isostar, Lucozade Sport Lemon, Lucozade Sport Orange, Maxim,...

Morgan's three students (Muller, Sturtevant, and Bridges) introduced reductionist empirical methods to the study of the chromosomal theory of heredity. Herman J. Muller concentrated on mutations, namely changes in the heterocatalytic properties of genes, without losing their autocatalytic (self-replication) properties. Experimental induction of mutations allowed quantitative analyses of genes' ...

In the emerging area of nanotechnology, a key issue is related to the potential impacts of the novel nanomaterials on the environment and human health, so that this technology can be used with minimal risk. Specifically designed to combine on a single structure multipurpose tags and properties, smart nanomaterials need a comprehensive characterization of both chemicophysical properties and adeq...

Several descriptors applied to peptide structure-activity and/or structure-property relationships have been developed in recent years. This report describes new descriptors for the natural amino acids which have been derived from the principal component analysis (PCA) applied on the MS-WHIM 3D-description matrices. MS-WHIM indexes are a collection of 36 statistical indexes aimed at extracting a...

Homeopathy has been continuously faced with the problem of explaining the therapeutic action of medicines diluted beyond the theoretical Avogadro limit of molecular presence. This paradox has lent weight to the hypothesis of solvent as a likely support of therapeutic action. Way back in 1941, Boyd (1) put forward the notion of physical modifications induced in the solvent, a notion which, in la...