نتایج جستجو برای: cga

تعداد نتایج: 1487  

Background and Objective: Chlorogenic acid (CGA) is a major polyphenolic component of coffee. Reduction in the risk of a variety of diseases following CGA consumption has been mentioned in recent studies. The effect of CGA on learning and memory in rats with cognitive deficit induced by intracerebroventricular streptozotocin (STZ) and  acetylchoinesterase (AChE) activity was evaluated in this s...

The main aim of this experimental work was to develop a separation process using micro- bubbles less than 100 µm in diameter. Micro-agglomerates were produced using 10kg crude oil/tone feed coal treated compared to 250 kg/tone feed coal treated for conventional spherical oil agglomeration. These micro-agglomerates were separated from the unagglomerated minerals by micro-bubble flotation. Colloi...

Journal: :Acta medica Indonesiana 2008
Czeresna Heriawan Soejono

AIM to investigate the cost effectiveness of CGA in an acute geriatric ward. METHODS a non-randomized controlled trial was carried out at Dr. Cipto Mangunkusumo General Hospital from January to December 2005. The inclusion criteria were elderly patients with geriatric syndrome. Exclusion criteria were advanced malignancy, APACHE II score > 34,in-hospital mortality in the first 24 hours, move ...

Journal: :Clinical chemistry 2007
Tine Børglum Jens F Rehfeld Lars B Drivsholm Linda Hilsted

BACKGROUND Most neuroendocrine tumors express chromogranin A (CgA). The posttranslational processing of neuroendocrine proteins such as CgA is often specific for the individual tumor. To cope with this variability and improve tumor diagnosis, we developed a processing-independent analysis (PIA) method to measure the total CgA product. METHODS For PIA, samples underwent trypsin treatment follo...

Nasrin Shayanfar, Shahriar Zohourian Shahzadi

Background and Objective: Neuroendocrine differentiation has not been proved to have effects in behavior of colorectal carcinomas. The aim of this study was Immunohistochemical evaluation of neuroendocrine differentiation in colorectal cancer. Patients and Methods: In this cross-sectional study, 83 paraffin blocks from patients admitted in Rasoul-e-akram Hospital, Tehran, Iran, during 2003 to ...

Journal: :Clinical chemistry 1999
T B Jensen L Hilsted J F Rehfeld

BACKGROUND Human chromogranin A (CgA) is an acidic protein widely expressed in neuroendocrine tissue and tumors. The extensive tissue- and tumor-specific cleavages of CgA at basic cleavage sites produce multiple peptides. METHODS We have developed a library of RIAs specific for different epitopes, including the NH2 and COOH termini and three sequences adjacent to dibasic sites in the remainin...

2014
Yu-hong Wang Qiu-chen Yang Yuan Lin Ling Xue Min-hu Chen Jie Chen Lu Wang.

Chromogranin A (CgA) not only plays an important role in pathologic diagnosis, but is also used as a circulating biomarker in patients with gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN). However, the relationship between immunohistochemistry (IHC) expression and serum levels of CgA has not been investigated. The value of CgA for evaluating treatment response and prognosis is still no...

Journal: :The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1992
G Lahr A Mayerhofer M Bergmann M A Takiyyuddin M Gratzl

Chromogranin A (CGA) is an abundant protein of dense-cored secretory vesicles in endocrine and neuronal cells. The present study, for the first time, compares CGA of neurons of the central nervous system with the CGA of adrenal origin. By S1 nucleus protection assay, we found that the 3' part of the CGA mRNA between exons 5-8 of the cerebellum and the spinal cord of the rat is homologous to tha...

Journal: :Molecules 2014
Hao-Rong Li Maidina Habasi Lian-Zhen Xie Haji Akber Aisa

Chlorogenic acid (CGA), the ester formed between caffeic acid and l-quinic acid, is a widespread phenolic compound. It is part of the human diet, found in foods such as coffee, apples, pears, etc. CGA is also was widely used in cosmetics, but the effects of CGA on melanogenesis are unknown. In this study, we analyzed the effects of CGA on cell proliferation, melanin content and tyrosinase of B1...

Journal: :European journal of endocrinology 2004
Giampaolo Bernini Angelica Moretti Vincenzo Fontana Cinzia Orlandini Paolo Miccoli Piero Berti Fulvio Basolo Pinuccia Faviana Michele Bardini Antonio Salvetti

OBJECTIVE To evaluate whether adenomas arising from the adrenal cortex, a tissue of epithelial origin, are associated with high chromogranin A (CgA) levels and whether such tumors may express and release this protein. In addition, to investigate whether high CgA levels imply a neuroendocrine differentiation of the adrenocortical adenomas and, therefore, represent a humoral marker of malignant t...

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