Journal:
:iranian journal of medical sciences
0
atefeh seghatoleslam recombinant protein laboratory, biochemistry department, medical school, shiraz university of medical sciences, shiraz, iran; and histomorphometry and stereology research center, medical school, shiraz university of medical sciences, shiraz, iran
mina hemmati recombinant protein laboratory, biochemistry department, medical school, shiraz university of medical sciences, shiraz, iran; and department of biochemistry, faculty of medicine, birjand university of medical sciences, birjand, iran
saeedeh ebadat recombinant protein laboratory, biochemistry department, medical school, shiraz university of medical sciences, shiraz, iran;
bahram movahedi recombinant protein laboratory, biochemistry department, medical school, shiraz university of medical sciences, shiraz, iran;
zohreh mostafavi-pour recombinant protein laboratory, biochemistry department, medical school, shiraz university of medical sciences, shiraz, iran; and maternal-fetal medicine research center, shiraz university of medical sciences, shiraz, iran
background: macrophage immune responses are affected by the secretory proteins of mycobacterium tuberculosis (mtb). this study aimed to examine the immune responses of macrophages to mtb secretory antigens, namely esat-6, cfp-10, and esat-6/cfp-10. methods: thp-1 cells (a human monocytic cell line) were cultured and differentiated to macrophages by phorbol 12-myristate 13-acetate. the cytotoxic...