Although cervical spondylotic myelopathy is a common cause of chronic spinal cord dysfunction in humans, little is known about the molecular mechanisms underlying the progressive neural degeneration characterized by this condition. Based on animal models of cervical spondylotic myelopathy and traumatic spinal cord injury, we hypothesized that Fas-mediated apoptosis and inflammation may play an ...

STUDY DESIGN National population-based cohort study. OBJECTIVE To compare the reoperation rates between cervical spondylotic radiculopathy and myelopathy in a national population of patients. SUMMARY OF BACKGROUND DATA There is an inherently low incidence of reoperation after surgery for cervical degenerative disease. Therefore, it is difficult to sufficiently power studies to detect differ...

Cervical spondylotic myelopathy can result from degenerative cervical spondylosis, herniated disk material, osteophytes, redundant ligamentum flavum, or ossification of the posterior longitudinal ligament. Surgical intervention for multi-level myelopathy aims to decompress the spinal cord and maintain stability of the cervical spine. Laminoplasty was major surgical advancement as laminectomy re...

purpose: this study investigated functionality statues and surgical outcome of patients with cervical spondylotic myelopathy (csm) contains cervical herniated disc (chd) and cervical spinal stenosis (css) based on the japanese orthopedic association cervical myelopathy evaluation questionnaire (joacmeq). methods: this was a prospective clinical study a sample of cases with csm. patient’s functi...

We reviewed 75 patients (57 men and 18 women), who had undergone tension-band laminoplasty for cervical spondylotic myelopathy (42 patients) or compression myelopathy due to ossification of the posterior longitudinal ligament (33 patients) and had been followed for more than ten years. Clinical and functional results were estimated using the Japanese Orthopaedic Association score. The rate of r...

STUDY DESIGN This was a retrospective study. PURPOSE The purpose of this study was to study the relationship between prevalence of pyramidal signs and the severity of cervical myelopathy. The study is focused on patients having increased signal intensity in T2-weighted magnetic resonance imaging. OVERVIEW OF LITERATURE Cervical spondylotic myelopathy is the most common cause of spinal cord ...

BACKGROUND Free tissue reconstruction after ablation of head and neck malignancy often requires extensive cervical manipulation, which may exacerbate preexisting cervical spondylosis and result in progression to cervical myelopathy. We present a rare case of postoperative quadriplegia caused by cervical spondylotic myelopathy after head and neck reconstruction. METHODS AND RESULTS A 63-year-o...

Principles of echo shifting with a train of observations was used to perform magnetic susceptibility-weighted magnetic resonance imaging with bolus-tracking in 14 patients with spondylotic myelopathy to assess changes in perfusion parameters of the spinal cord before and after decompression surgery for cervical spondylotic myelopathy. The mean transit time (MTT), bolus arrival time (T0), and ti...

BACKGROUND Diabetes is one of the most frequent comorbidities in patients with cervical spondylotic myelopathy. The purpose of this study was to characterize the risk factors for poor treatment outcome following cervical laminoplasty for cervical spondylotic myelopathy in patients with diabetes. METHODS A total of 105 consecutive patients with diabetes and cervical spondylotic myelopathy who ...

Degenerative cervical spondylosis is a common, mostly asymptomatic condition, occurring as a result of age-related degenerative changes in the cervical spine. Symptoms caused by cervical spondylosis can be categorized broadly into three clinical syndromes: axial neck pain, cervical radiculopathy, and cervical myelopathy; with patients commonly having a combination of these syndromes. This speci...