background:  intravenous  recombinant  tissue plasminogen  activator  (rt-pa) is an approved  treatment for acute ischemic stroke within 4.5 h of symptoms onset. decompressive craniectomy (dc) has been  shown  as an effective  therapeutic  modality in malignant  middle cerebral  artery (mca) infarction. as rt-pa could result in hemorrhagic  complication during or after any surgery dc may be ass...

background: although the risk factors of ischemic strokes are well defined, there is slight information about their relations with the etiologies of ischemic strokes. this study investigated the distribution of ischemic stroke risk factors and their connections to diverse etiologies of cerebrovascular attack (cva) and specific ischemic regions of brain. methods: in this cross sectional study , ...

post stroke dementia is one of the most common complications of stroke that is preventable and relatively treatable too. the purpose of the study is comparison between the positive findings in brain ct scan and brain perfusion spect. 15 patients who were complicated by dementia after cerebrovascular accident and also 5 patients as a control group enrolled in this study. brain ct scan and brain ...

introduction: cerebral venous-sinus thrombosis (cvst) is a life threatening condition that needs rapid diagnosis and treatment. it appears comparatively more common in middle east and south asia. objectives: to determine the demographic, clinical patterns, etiologies and prognostic factors of cvst in the north east of iran. materials and methods: all adult patients admitted with a documented di...

background: stroke is a multifactorial disorder, the most common cause being arterial occlusion. transcranial doppler ultrasonography (tcd) is a common non-invasive method available for assessment the arterial blood flow of the brain. objective: assessment the hemodynamic parameters of cerebral arteries, using tcd device in patients suffering ischemic stroke. materials and methods: this descrip...

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Objective(s): Stroke is known as a main cause of mortality and prolonged disability in adults. Both transient receptor potential V1 (TRPV1) channels and toll-like receptors (TLRs) are involved in mediating the inflammatory responses. In the present study, the effects of TRPV1 receptor activation and blockade on stroke outcome and gene expression of TLR2 and TLR4 were assessed following permanen...

background: hyperthyroidism as a risk factor for stroke is not conclusive. there are no definite data on the relationship between ischemic cerebrovascular injury and hyperthyroidism. this study was designed to define whether the outcomes of post-ischemic stroke injury are influenced by chronic hyperthyroidism. methods: two groups of hyperthyroid (ht) and control euthyroid rats of equal numbers ...

background: we aimed to research the value of extended nursing for cerebral stroke patients within a suitable recovery empty period. methods: seventy-two cerebral stroke patients were randomized to a control group or treatment group at the recovery period at xuzhou recovery hospital, china in 2016. a recovery guidance exercise was applied to the control group for a set time, while a recovery gu...

Introduction: TRPV1 is a non-selective cation channel with high permeability to calcium ions, and is also involved in the development of neurogenic and inflammatory pain. The increase in intracellular calcium plays a role in worsening of stroke. In the present study we investigated the effect of (AMG9810) TRPV1 receptor antagonist on stroke outcome in the permanent middle cerebral artery occlus...