Cerebrovascular disease is one of the leading causes of death in the world, and about one-fourth of cerebrovascular deaths are due to ruptured cerebral aneurysms (CA). Hence it is important to find a way to reduce aneurysm formation and its subsequent morbidity and mortality. Proteolytic activity capable of lysing gelatin has been shown to be increased in aneurysm tissue and expressio...

background: aneurysm is a blood-filled bulge in the wall of vessels that occurred in abdominal aortic and cerebral vessels. the dilation of artery leads to aneurysm. methods: three dimensional modelling was utilized for a patient with cerebral aneurysm and a normal subject, and additional fluid-structural interaction simulation was performed. we consider pulsatile blood velocity as inlet, and b...

Background: Cerebral aneurysm disease causes intracranial hemorrhage by rupturing, which can eventually, lead to organ failure or death. For this reason, it is important to anticipate the reasons for rupturing of a cerebral aneurysm from biomechanical point of view. Investigating this disease may even help the physicians to find treatments and predict the patient’s situation. This research was ...

cerebrovascular disease is one of the leading causes of death in the world, and about one-fourth of cerebrovascular deaths are due to ruptured cerebral aneurysms (ca). hence it is important to find a way to reduce aneurysm formation and its subsequent morbidity and mortality. proteolytic activity capable of lysing gelatin has been shown to be increased in aneurysm tissue and expression of plasm...

Background and Aim: In-hospital rebleeding and early aneurysm rupture are major causes of mortality and morbidity in aneurysmal subarachnoid hemorrhage. Rebleeding may occur at the referring hospital, during transfer or at the referral neurovascular center prior to surgical or endovascular treatment. However, there has been no report regarding the rate of in-hospital rebleeding and early aneury...

It is the key step of the cerebral aneurysm recognition system to locate the cerebral aneurysm accurately and fast onto the image. A new detection method of cerebral aneurysm, which is based on the improved thinning algorithm, is proposed after analyzing the morphological characteristics of cerebral aneurysm fully in the paper. In this new detection method, the improved OPTA algorithm is used t...

Subarachnoid hemorrhage due to the rupture of a cerebral aneurysm is a life-threatening disease. Despite this, the detailed mechanisms underlying the initiation and progression of cerebral aneurysm are unclear. The relation of hypercholesterolemia and apolipoprotein E (ApoE) to cerebral aneurysm formation, has been unclear until now. We used, in the present study, a previously established cereb...