The lecithins and cephalins are complex mixtures of chemical entities differing from each other (a) in their component fatty acids, (h) in the case of the cephalins, in the nitrogenous constituent, and (c) in the point of substitution of t.he phosphoric acid-base group in the molecule. Power and Tutin (I) were the first to question the uniformity of the glycerophosphoric acids of lecithin. In 1...

The investigation of the structure of the lecithins and cephalins (phosphatidylethanolamines) from natural sources gave rise to the question, whether the phosphoric acid in these substances is attached to the (Yor P-carbon atom of the glycerol moiety. Since the acid and alkaline hydrolysis of natural lecithins yielded mixtures of CYand p-glycerophosphoric acid (GPA), it was assumed that they ex...

In 1944, Taurog et al. (1) pointed out that practically all of the phospholipides in plasma of man and dog contain choline. This indicates that the plasma phospholipides of these two species consist almost entirely of lecithins and sphingomyelins. Confirmation of this finding has now come from Hack (2) and from Sinclair (3-5). The former reported that about 95 per cent of the phospholipides in ...

In 1944, Taurog et al. (1) pointed out that practically all of the phospholipides in plasma of man and dog contain choline. This indicates that the plasma phospholipides of these two species consist almost entirely of lecithins and sphingomyelins. Confirmation of this finding has now come from Hack (2) and from Sinclair (3-5). The former reported that about 95 per cent of the phospholipides in ...

In the plasma of patients with acute myocardial infarction the values for phosphatidyl ethanolamine are on the average 50% to 100% higher than in patients with chronic coronary heart disease and up to 400% higher than in normal individuals. Those for phosphatidyl serine are about 50% higher than in patients with chronic coronary heart disease and up to 300% higher than in normal individuals. Ex...