conclusions fmf should be considered in patients who present with alopecia, acne like lesions, cysts and comedones in older ages with a spectrum of histologic changes. we emphasize for any time it should be under-recognized. introduction folliculotropic mycosis fungoides (fmf) is a variant of mycosis fungoides characterized by the presence of folliculotropic atypical tcells infiltrates, often w...

Angioimmunoblastic T-cell lymphoma associated with leukocytosis and lymphocytosis; a case report systematic review

BACKGROUND Monoclonal B-cell lymphocytosis is classified as 'high-count or clinical' monoclonal B-cell lymphocytosis and 'low-count or population' monoclonal B-cell lymphocytosis. Previously, 167 first-degree relatives pertaining to sporadic (non-familial) chronic lymphocytic leukemia families were studied and the presence of seven monoclonal B-cell lymphocytosis individuals was reported. OBJ...

BACKGROUND Malignant thymomas are rarely associated with bone metastasis and T-cell lymphocytosis. CASE PRESENTATION A 47-year-old female patient was admitted to our hospital for ptosis. A diagnosis of malignant thymoma was made based on the thymectomy and pathological result. Peripheral T-cell lymphocytosis and bone metastasis were found later. T-cell lymphocytosis was relived after surgical...

BACKGROUND Evidence suggests that monoclonal B-cell lymphocytosis precedes all chronic lymphocytic leukemia cases, although the molecular mechanisms responsible for disease progression are not understood. Aberrant miRNA expression may contribute to the pathogenesis of chronic lymphocytic leukemia. The objective of this study was to compare miRNA expression profiles of patients with Binet A chro...

Monoclonal B-cell lymphocytosis (MBL) is an asymptomatic hematologic condition defined by the presence of a small (<5 x 10(9)/L) clonal B-cell population in the peripheral blood in the absence of lymph-node enlargement, cytopenias or autoimmune diseases. It is found in approximately 3-12% of normal persons depending on the accuracy of analytical techniques applied. According to the immunophenot...

Hairy B-cell lymphoproliferative disorder (HBLD) is one of chronic polyclonal B-cell lymphocytosis. We report a 47-year-old female Japanese patient diagnosed as having HBLD based on lymphocytosis with hairy cell appearance and characteristic phenotypes including CD11c+ and without B-cell monoclonality. She was a non-smoker and possessed HLA-DR4. She has been closely followed up without treatmen...

Chronic B-cell lymphocytic leukemia (B-CLL) represents 0.9% of all new cancers. It is estimated that there will be almost 15 000 new cases and 4600 deaths due to CLL in 2015 in the USA.1 The median ages at diagnosis and death are 71 years and 80 years, respectively.1 The criteria that define the diagnosis of B-CLL include the presence of at least 5 × 106 B lymphocytes/L with the peculiar CLL ph...

BACKGROUND Canine lymphoproliferative disease often presents with lymphocytosis and is immunophenotypically diverse. HYPOTHESIS Immunophenotype predicts prognosis in canine lymphoproliferative disorders involving circulating lymphocytosis. ANIMALS Dogs that had peripheral blood evaluation performed by flow cytometry by the Clinical Immunology Service at Colorado State University between 200...