نتایج جستجو برای: cell free assay

تعداد نتایج: 2242664  

Journal: :research journal of pharmacognosy 0
m. mojarrab pharmaceutical sciences research center, school of pharmacy, kermanshah university of medical sciences, kermanshah, iran. s.a. emami depertment of pharmacognosy, faculty of pharmacy, mashhad university of medical sciences, mashhad, iran. sh. gheibi pharmaceutical sciences research center, school of pharmacy, kermanshah university of medical sciences, kermanshah, iran. a.m. taleb department of pharmacogenesis, faculty of pharmacy, tehran university of medical sciences, tehran, iran. f. heshmati afshar drug applied research center, tabriz university of medical sciences, tabriz, iran. department of pharmacognosy, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran.

background and objectives:the plants of genus artemisia (asteraceae) have been conventionally used for prevention and medication of a number of ailments. in the present research, ten extracts with different polarities from aerial parts of two artemisia species, a. kopetdaghensis and a. turcomanica were evaluated for their potential anti-malarial properties. methods: the plant materials were ext...

  Background :Wide distribution and low half-life of acyclovir has led to a high dose consumption of the drug. Recent studies have shown that encapsulation of acyclovir in nano-carriers can increase effectiveness and decrease its side effects. We investigated the inhibitory effect of acyclovir loaded nano-niosomes against herpes simplex virus type-1 (HSV-1) in cell culture.   Methods : In-vitro...

Journal: :medical journal of islamic republic of iran 0
seyed hamidreza monavari department of virology, school of medicine, iran university of medical sciences,tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences) mohammad javad mirzaeiparsa school of advanced medical technologies, tehran university of medical sciences,tehran, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences) bahram bolouri school of advanced medical technologies, iran university of medical sciences,tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences) soltan ahmed ebrahimi department of pharmacology, school of medicine, iran university of medical scinces,tehran, iran. angila ataei-pirkooh department of virology, school of medicine, iran university of medical sciences,tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences)

background :wide distribution and low half-life of acyclovir has led to a high dose consumption of the drug. recent studies have shown that encapsulation of acyclovir in nano-carriers can increase effectiveness and decrease its side effects. we investigated the inhibitory effect of acyclovir loaded nano-niosomes against herpes simplex virus type-1 (hsv-1) in cell culture.   methods : in-vitro c...

Journal: :کنترل بیولوژیک آفات و بیماری های گیاهی 0
حمیده افشارمنش استادیار، پژوهشکدۀ کشاورزی هسته ای، پژوهشگاه علوم و فنون هسته ای، صندوق پستی 498-3148، کرج مسعود احمدزاده استاد، گروه گیاه پزشکی، پردیس کشاورزی و منابع طبیعی، دانشگاه تهران، صندوق پستی 77871-31587، کرج

members of the genus bacillus are among the most promising candidates for biological control of plant pathogenic bacteria. in this study, cell free supernatants of three strains b. subtilis utb96, b. subtilis utb1 and b. subtilis utb70 against aspergillus flavus r5 were investigated using dual culture assay. strain b. subtilis utb96 showed the highest inhibition effect. thin lyer chromatography...

Journal: :مجله دانشگاه علوم پزشکی شهید صدوقی یزد 0
محمد شکر زاده m shokrzadeh فرشاد حسینی شیرازی f hosseini- shirazi سهیل سعیدی ساروی s saeedi saravi

introduction: cell culture is a process in which the cells ware isolated from original tissue, dispersed in liquid media and then placed in culture plate where the cells adhere together and propagate. today, this method is used for assessment of cell toxicity, its mechanisms and effect of different compounds on intracellular components. methods: clonogenic assay was used for assessment of cell ...

Journal: :research journal of pharmacognosy 2014
m. hamzeloo-moghadam n. taiebi m. mosaddegh b. eslami tehrani s. esmaeili

improving the solubility of non-soluble herbal materials is an issue of interest in cell culture based experiments. evaluating the biological activity of these materials could become possible with the aid of cosolvents/surfactants which obviously should have little or no cytotoxic activity. in the present study, the cytotoxic activity of six cosolvents/surfactants: ethanol, methanol, tween 20 a...

Journal: :research in molecular medicine 0
fatemeh amiri university -sari fatemeh moradian sari agricultural sciences and natural resources university -sari alireza rafiei medical sciences university- sari

background: lactoferrin is a glycoprotein with a molecular weight of 80 kda, as a member of the transferring family. in recent investigations the important biological properties such as anti microbial, antiviral and anticancer activity of lactoferrin were studied. in the present study, the effect of antitumor induced by lactoferin was evaluated on stomach cancer cell ags. materials and methods:...

Journal: :iranian journal of pharmaceutical research 0
mansour rismanchian dental implant research center and prosthodontics, school of dentistry, isfahan university of medical sciences, isfahan, ir iran. niloufar khodaeian dental materials research center and prosthodontics, school of dentistry, isfahan university of medical sciences, isfahan, ir iran. lida bahramian dental implant research center and prosthodontics, school of dentistry, isfahan university of medical sciences, isfahan, ir iran. mohammad hosein fathi biomaterials research group, department of materials engineering, isfahan university of technology, isfahan, ir iran. hojjat sadeghi-aliabadi department of medicinal chemistry, school of pharmacy, isfahan university of medical sciences, isfahan, ir iran.

the cytotoxicity of the biomaterials is a key issue that should be addressed prior to pre-clinical applications. this study was designed to evaluate and compare the cytotoxixity of two forms of bioactive glasses:nanopowder:andmicropowder. human hgf1-pi53 gingival fibroblast cells were used to evaluate the cytotoxicity of 0.5, 1, 1.5, 2, 5, 10, 15 and 20 mg/ml concentrations of the two bioactive...

Journal: :avicenna journal of phytomedicine 0
soheila sepahi department of pharmacology, isfahan pharmaceutical sciences research center, school of pharmacy and pharmaceutical sciences, isfahan university of medical sciences, isfahan, iran. abbas jafarian-dehkordi department of pharmacology, isfahan pharmaceutical sciences research center, school of pharmacy and pharmaceutical sciences, isfahan university of medical sciences, isfahan, iran. maryam mirlohi food security research centre, school of nutrition and food sciences, isfahan university of medical sciences, isfahan, iran kobra shirani department of pharmacodynamy and toxicology, faculty of pharmacy, mashhad university of medical sciences, mashhad, iran. mahmoud etebari department of pharmacology, isfahan pharmaceutical sciences research center, school of pharmacy and pharmaceutical sciences, isfahan university of medical sciences, isfahan, iran.

objective: irinotecan is a botanical derivative and an anti-cancer drug with cytotoxic and genotoxic effects. the present study evaluated the effect of lactobacillus plantarum a7 on the genotoxic activity of irinotecan in a hepatocellular carcinoma cell line (hepg2) by comet assay. materials and methods: hepg2 were incubated with irinotecan (100 µm), heat-killed cells (0.025 µg/ml) + irinotecan...

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