نتایج جستجو برای: cd64

تعداد نتایج: 573  

Journal: :Experimental & molecular medicine 2018
Jiyoun Min Dongchan Yang Sung Mirang Kim Keeok Haam Anji Yoo Jae-Hoon Choi Barbara U Schraml Yong Sung Kim Dongsup Kim Suk-Jo Kang

The spatiotemporal regulation of immune cells in lymph nodes (LNs) is crucial for mounting protective T-cell responses, which are orchestrated by dendritic cells (DCs). However, it is unclear how the DC subsets are altered by the inflammatory milieu of LNs. Here, we show that the inflamed LNs of Listeria-infected mice are characterized by the clustering of neutrophils and monocytes and IFN-γ pr...

Journal: :Open access emergency medicine : OAEM 2014
Andrea Cortegiani Vincenzo Russotto Francesca Montalto Grazia Foresta Pasquale Iozzo Santi Maurizio Raineri Antonino Giarratano

INTRODUCTION Cluster of differentiation 64 (CD64) is expressed on neutrophils during bacterial infections and sepsis. The aim of our study was to assess the CD64 expression in patients admitted to the emergency department (ED) with a triage diagnosis of acute respiratory failure (ARF) and/or dyspnea and to verify a relationship between its value and the presence of infection. METHODS We asses...

Journal: :Journal of immunology 2006
Anneke J van Vuuren Joel A G van Roon Vanessa Walraven Ilonka Stuij Martin C Harmsen Pamela M J McLaughlin Jan G J van de Winkel Theo Thepen

Macrophages are known to play a key role during inflammation in rheumatoid arthritis (RA). Inflammatory macrophages have increased expression of CD64, the high-affinity receptor for IgG. Targeting this receptor through a CD64-directed immunotoxin, composed of an Ab against CD64 and Ricin A, results in effective killing of inflammatory macrophages. In this study, we show elevated levels of CD64 ...

2014
Hao Zhang Xian-Long Ling Yu-Yun Wu Mu-Han Lü Hong Guo Peng-Bin Zhang Xiao-Yan Zhao Shi-Ming Yang

BACKGROUND/AIMS Upregulated CD64 expression on neutrophils is the most useful marker for acute bacterial infections and systemic inflammation. However, it is unknown whether CD64 is involved in the pathogenesis of acute pancreatitis (AP). This study was designed to determine whether CD64 is implicated in severe acute pancreatitis (SAP), and thus, is a suitable marker for SAP. METHODS SAP was ...

2014
Jikun Du Li Li Yuhong Dou Peipei Li Rui Chen Helu Liu

INTRODUCTION Neutrophil CD64 has been proposed as an early marker of sepsis. This study aims to evaluate the diagnostic utility of neutrophil CD64 for identification of early-onset sepsis in preterm neonates. METHODS The prospective study was conducted in a neonatal intensive care unit between November 2010 and June 2011. Preterm neonates in whom infection was suspected when they were <12 hou...

Journal: :European journal of immunology 1997
E Grage-Griebenow J Baran H Loppnow M Los M Ernst H D Flad J Pryjma

It has been demonstrated that in monocyte/T cell co-cultures activated with recall antigens, cytotoxic T cells were generated which are able to reduce the number of antigen-presenting monocytes. In previous studies we could show that a minor subset of monocytes, the Fc gamma receptor I-negative (CD64-) monocytes, exhibits significantly higher antigen-presenting capacity than the main population...

2012
Young Kwang Choo Hyun-Seok Cho In Bum Seo Hyeon-Soo Lee

PURPOSE Early identification of neonatal sepsis is a global issue because of limitations in diagnostic procedures. The objective of this study was to compare the diagnostic accuracy of neutrophil CD64 and C-reactive protein (CRP) as a single test for the early detection of neonatal sepsis. METHODS A prospective study enrolled newborns with documented sepsis (n=11), clinical sepsis (n=12) and ...

Journal: :International journal of clinical and experimental medicine 2015
Hao Feng Jie Yin Ya-Ping Han Xiao-Ying Zhou Guo-Xin Zhang

CD64 was up-regulated in infection diseases, but there was no report about the change of CD64 in chronic hepatitis B virus (HBV) infection. The purpose of this study was to determine whether there was a dynamic change of CD 64 index and to judge the value to antiviral treatment. 96 CHB patients were enrolled and selected 33 healthy adults as control. We detected the level of CD64, found the lev...

Journal: :Journal of infection in developing countries 2015
Dai-Hua Fang Cong-Hai Fan Juan Li Qi An Hong Yao Qiang Ji Gao Niu

INTRODUCTION Neutrophil CD64 expression has been demonstrated as an improved diagnostic marker of infection and sepsis. The purpose of this study was to develop a new method to evaluate neutrophil CD64 expression for diagnosis of neonatal sepsis. METHODOLOGY Eighty neonates with neonatal sepsis (21 culture positive, 59 negative) were enrolled in this prospective study along with 19 neonates w...

2015
Florian Kipfmueller Jessica Schneider Julia Prusseit Ioanna Dimitriou Berndt Zur Axel R. Franz Peter Bartmann Andreas Mueller

INTRODUCTION The role of CD64 in late onset sepsis (LOS) in preterm infants has been described in several studies. Aim of this study was to investigate whether CD64 expression is increased in the days before clinical manifestation of LOS. METHODS Patients with birth weight below 1,500 g were eligible for study participation. During routine blood sampling CD64 index was determined between day ...

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