نتایج جستجو برای: cbs2
تعداد نتایج: 11 فیلتر نتایج به سال:
The cystathionine β-synthase module of OpuA in conjunction with an anionic membrane surface acts as a sensor of internal ionic strength, which allows the protein to respond to osmotic stress. We now show by chemical modification and cross-linking studies that CBS2-CBS2 interface residues are critical for transport activity and/or ionic regulation of transport, whereas CBS1 serves no functional ...
The analysis of the 269 open reading frames of yeast chromosome VIII by computational methods has yielded 24 new significant sequence similarities to proteins of known function. The resulting predicted functions include three particularly interesting cases of translation-associated proteins: peptidyl-tRNA hydrolase, a ribosome recycling factor homologue, and a protein similar to cytochrome b tr...
This research assessed the shrinkage behavior of mortar containing recycled sand generated from aerated blocks and clay bricks by replacing natural with a volume ratio 30%. Five mix proportions were prepared to cast plate specimens. They named as control, ABs1, ABs2, CBs1 CBs2. Among them, ABs1 CBs1, respectively, have same water/cement control. ABs2 CBs2 had workability control adjusting requi...
MOTIVATION Transcription factor binding sites often differ significantly in their primary sequence and can hardly be aligned. Often one set of sites can contain several subsets of sequences that follow not just one but several different patterns. There is a need for sensitive methods to reveal multiple patterns in unaligned sets of sequences. RESULTS We developed a novel method for analysis o...
•An elongated region of the Drosophila TRP tail specifically binds to Ca2+-CaM•Two discrete fragments N- and C-lobes Ca2+-CaM•Unexpectedly, CaM binding does not directly modulate channel activity•Mammalian TRPC4 Ca2+-CaM with a similar mode as is calcium-permeable cation essential for fly visual signal transduction. During phototransduction, Ca2+ mediates both positive negative feedback regulat...
Phosphatases of regenerating liver (PRLs), the most oncogenic of all protein-tyrosine phosphatases (PTPs), play a critical role in metastatic progression of cancers. Recent findings established a new paradigm by uncovering that their association with magnesium transporters of the cyclin M (CNNM) family causes a rise in intracellular magnesium levels that promote oncogenic transformation. Recent...
Chloride-proton exchange by the lysosomal anion transporter ClC-7/Ostm1 is of pivotal importance for the physiology of lysosomes and bone resorption. Mice lacking either ClC-7 or Ostm1 develop a lysosomal storage disease and mutations in either protein have been found to underlie osteopetrosis in mice and humans. Some human disease-causing CLCN7 mutations accelerate the usually slow voltage-dep...
The aim of this study was the development and characterization of lipid nanocarriers using food grade components for oral delivery of Serenoa repens CO2 extract, namely microemulsions (MEs) and self-microemulsifying drug delivery systems (SMEDDSs) to improve the oral absorption. A commercial blend (CB) containing 320 of S. repens CO2 extract plus the aqueous soluble extracts of nettle root and ...
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