spirometry has been used as a common diagnostic test in asthma. most of the patients with a mild asthma have a fev1 within normal range. hence, other diagnostic methods are usually used. the aim of this study was to evaluate whether eosinophil cationic protein (ecp) could be an accurate diagnostic marker of mild asthma. in this study diagnosis of asthma was made according to internationally acc...

In this paper, synthesis and antimicrobial properties of cationic dye were investigated. 4-acetylamino-N-2-aminomethylpyridine-1,8-naphthalimide was reacted with 1-bromobutane as the alkylating agent and a cationic dye was obtained. The final product was purified by column chromatography method. The chemical structure of the novel cationic dye and its intermediates was chracterisized by using F...

cationic copolymer gels of acrylamide and [(methacrylamido) propyl] trimethyl ammonium chloride (maptac) were synthesized by free radical aqueous solution polymerization. the taguchi method, a robust experimental design, was employed for the optimization of the synthesis based on the equilibrium swelling capacity of the hydrogels. based on taguchi method a standard l16 orthogonal array with fiv...

The preclinical in vitro and in vivo benchmark figures of cationic antimicrobial peptides have to be revisited based on the newly discovered alternative modes of action.

A single animal can express several cationic antimicrobial peptides with different sequences and structures. We demonstrate that mammalian peptides from different structural classes frequently show synergy with each other and selectively show synergy with human lysozyme.

Over the past decade, levels of bacterial resistance to antibiotics have risen dramatically and "superbugs" resistant to most or all available agents have appeared in the clinic. Thus there is a growing need to discover and introduce new drugs. One potential source of novel antibiotics is the cationic antimicrobial peptides, which have been isolated from most living entities as components of th...

in this study, aggregation behavior of a water soluble cationic metalloporphyrin, meso-tetrakis (2,3,5,6-tetrafluoro-n,n´,n´´-trimethyl ammonium phenyl) porphyrin nickel(ii) [ni(ii)(tf4tmapp)]4+ is investigated in 5 mm aqueous phosphate buffer of ph 7.0 at 25.0 °c and various ionic strengths using optical absorption and resonance light scattering spectroscopic methods. the results suggest that ...

grafting polymerization was a valuable method for the modification of the chemical and physical properties of polymer surfaces. in this paper, the grafting of cationic vinyl monomer with quaternary ammonium groups, methacryloxyethyltrimethyl ammonium chloride (dmc), onto the isotactic polypropylene (ipp) granule was performed by suspension solid-state grafting process. the technique offers new ...