statement of problem: the casein phospho peptide-amorphous calcium phosphate with or without fluoride (cpp-acpf and cpp-acp respectively) are of considerably new materials which are highly recommended for prevention of dental caries. however, there is a shortage in literature on how they affect the ion concentration of saliva or dental plaque. objectives: the aim of this study was to evaluate t...

A phospho-oligosaccharide, whose production is stimulated by insulin, modulated the activity of partially purified casein kinase II. Whereas at 2 microM the phospho-oligosaccharide stimulated casein kinase II 1.3-fold, higher concentrations of this molecule were inhibitory. 50% inhibition of the enzyme was obtained at 15 microM phospho-oligosaccharide. This biphasic effect of the phospho-oligos...

milk is an important component of a balanced diet and contains many valuable constituents. a considerable part of the milk healthbenefits is related to its proteins, not only for their nutritive value but also for their biological properties. scientific evidence suggests that anticarcinogenic activities, antihypertensive properties, immune system modulation, and other metabolic features of milk...

Objective: to determine the effect of nano-hydroxyapatite and different bioactive remineralizing agent in treatment loss enamel minerals. Material M nano-hydroxyapatite, Casein phospho-peptide amorphous calcium phosphate Sodium Fluoride. While artificial saliva was applied on control specimens. Surface microhardness measurements baseline were calculated, before/after demineralization digital 3D...

A synthetic peptide having the sequence Arg-Arg-Arg-Glu-Glu-Thr-Glu-Glu-Glu was found to serve as a convenient substrate for the protein kinase generally referred to as casein kinase II. The enzyme exhibited an apparent Km of 500 microM for the peptide, as compared to an apparent Km of 50 microM for casein. The maximum velocities for phosphorylation of the peptide and of casein were similar. Th...

Transcription factor IIIA (TFIIIA), isolated from the cytoplasmic 7 S ribonucleoprotein complex of Xenopus oocytes, is phosphorylated when incubated with [gamma-(32)P]ATP. This modification is due to a trace kinase activity that remains associated with the factor through several steps of purification. The kinase can use either ATP or GTP, and will phosphorylate casein and phosvitin to the exclu...

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a mammary gland carcinogen in cooked meat. Using the HC11 mouse mammary epithelial cell line, a well-characterized model for hormone-mediated differentiation, we examined whether PhIP altered the expression of genes regulated by lactogenic hormones dexamethasone, insulin, and prolactin (DIP). When HC11-Lux cells (stably transfected with ...