objective(s): to study the effect of cardiopulmonary bypass (cpb) on nuclear factor-kappa b (nf-кb) and cytokine expression and pulmonary function in dogs. materials and methods: twelve male mongrel dogs were divided into a methylprednisolone group (group m) and a control group (group c). all animals underwent aortic and right atrial catheterization under general anesthesia. changes in pulmonar...

Cardiac surgery is associated with the development of a systemic inflammatory response. The cytokine response in cardiac surgery patients is well explained and is dominated by the pro-inflammatory cytokines tumour necrosis factor (TNF-α), interleukin-6 (IL-6), interleukin-8 (IL-8), and the antiinflammatory cytokine interleukin-10 (IL-10). The release of these cytokines has been related to the d...

conclusions our study showed superiority of off-pump cabg regarding lvef, rvef and valves regurgitations. future studies with prospective structure, accurate randomization, longer follow up duration, and larger sample size are needed. results one hundred eighteen patients with the mean age of 59.47 ± 9.68 years were included (81 male and 37 female). on-pump cabg was done on 84 patients and off-...

the present study was undertaken to compare the in hospital results of coronary artery bypass graft (cabg) with (on pump) or without (off pump) cardiopulmonary bypass (cpb). data were collected on all first-time isolated cabgs with saphenous vein and/or artery grafts at shahid madani hospital in tabriz-iran, between 2006 and 2009. age and clinical profile were marched between on pump and off pu...

conclusions administration of albumin compared to hes in patients with a normal renal function results in a lower drop of gfr and platelet count, less bleeding and lower rise of serum creatinine. background the ideal strategy to prime the cardiopulmonary bypass (cpb) circuit in adult cardiac surgery is still a matter of debate. objectives in this retrospective study, we examined albumin solutio...

conclusions in cabg with cardiopulmonary bypass, using plasma cortisol level as a measure, isoflurane-sufentanil significantly reduces the stress response to the surgery, when compared to propofol-sufentanil. results compared to the baseline (t0), at the end of cardiopulmonary bypass (t1), both groups demonstrated a decrease in plasma cortisol levels with no statistical significant difference (...

introduction: as off pump coronary artery bypass grafting surgery (cabg) is a developing method in coronary cardiac surgery, most surgeons are anxious about the danger of emergency crash conversion. in this observational study we tried to show the rate and outcome of conversion . material and methods: in this descriptive study about 477 coronary off-pump cabg patients were operated in ghaem hos...

conclusions: in the present study, applying positive airway pressure methods (cpap or imv) during cpb was associated with better postoperative abg measurements and (a-a) do2. results: the demographic data were similar in between three groups. graft number, pump time and preoperative abgs were not significantly different. postoperative pao2 were significantly higher in the cpap and imv groups an...

conclusions systemic arterial leukocyte filtration reduces the intubation time but has no other beneficial effect on the outcome of patients undergoing cabg or valve surgery. results the postoperative intubation time was significantly shorter in patients with leukocyte filters (0.014). there was no significant difference between two groups regarding other outcome relatedvariables. patients and ...