Hamilton, P Dow. Washington, DC , American Physiological Society, 1963, pp 1160-1161 2. Jones AW Altered ion transport in vascular smooth muscle from spontaneously hypertensive rats: influences of akiosterone, norepinephrine, and angiotensin. Circ Res 33: 563-572, 1973 3. Friedman SM: An ion-exchange approach to the problem of inlracellular sodium in the hypertensive process. Circ Res 34 (suppl...

using samples from 53 patients (mean age 66 y, range 37 to 88 y) with clinically and histologically confirmed cobrectal carcinoma and 12 patients (mean age 55 y, range 29 to 73 y) with other forms of cancer (nine gastric, two breast, and one ovarian). The in-house method was a double-antibody technique based upon a previously described method (2). We used only patients’ sera with increased in-h...

conclusions gallic acid and csa combination improved antioxidant capacity and cell membrane integrity more than each one alone. therefore, it can be a therapeutic approach to reduce the i/r injury. background myocardial infarction is one of the important causes of death during old ages. gallic acid as an antioxidant or cyclosporine a (csa) as inhibitor of mitochondrial permeability transition p...

Methamphetamine (MET) is a stimulant and one of the most abused drugs in worldwide. MET could cause several organ toxicity such as cardiotoxicity. Oxidative stress has been proposed as the main mechanism for MET toxicity. Propofol as a sedative-hypnotic agent has antioxidant property. In this study, we used propofol for attenuating of MET-induced cardiotoxicity in rats. The groups (six rats in ...

Serum cardiac enzyme levels (CK, LDH, SGOT) were estimated and the ECG recorded for 4 days following admission of 288 patients (Group I) to a stroke intensive care unit. Sixty-four of these patients, subsequently found not to have strokes, served as controls. Mean serum levels of all 3 cardiac enzymes were elevated in 8% of the 224 patients with stroke. The mean serum enzyme levels in patients ...

doxorubicin (dox) is an anthracycline antibiotic with broad spectrum anti-tumour activity. its effectiveness has been limited by the occurrence of dose-related myocardial and bone marrow toxicity. as oxidative stress is the main factor in dox-induced cardiotoxicity, we presumed that agents which enhance endogenous antioxidants can prevent dox induced cardiotoxicity. animals received either dox ...

The 4-ACGC isolated from BP was prepared to investigate the cardioprotective effects on attenuating chronic heart failure in vivo and in vitro. A chronic heart failure (CHF) rat model was established to investigate the cardioprotective effects of 4-ACGC. From this, several cardiac function indexes were recorded. The inflammatory markers including tumor necrosis factor-α (TNF-α), Interleukin-6 (...

Doxorubicin (DOX) is an anthracycline antibiotic with broad spectrum anti-tumour activity. Its effectiveness has been limited by the occurrence of dose-related myocardial and bone marrow toxicity. As oxidative stress is the main factor in DOX-induced cardiotoxicity, we presumed that agents which enhance endogenous antioxidants can prevent DOX induced cardiotoxicity. Animals received either DOX ...