We trapped a rat (Rattus norvegicus) infected with Capillaria hepatica. At necropsy, grossly yellowish-white nodules (2-3 mm in diameter) were noted to be scattered on the liver's surface. Microscopically, granulomatous and fibrotic nodules that contained the eggs and/or adult worms of Capillaria hepatica were detected in the liver. Septal fibrosis was diffusely formed throughout the liver. The...

In this paper, a serological assay for the detection of antibodies to Capillaria hepatica, a zoonotic parasite, is described. In the past, the only way of detecting Capillaria hepatica was to perform a liver biopsy. The indirect immunofluorescence (IIF) assay, based on liver sections of naturally infected mice and human serum samples, is suitable for detecting early stages of human infections a...

conclusions capillaria hepatica should be considered in differential diagnoses in any child with fever, hepatomegaly, eosinophilia and hyperglobulinemia. case presentation the current paper reports a case of capillaria hepatica infection in a four-year-old boy which presented with fever, hepatomegaly, peripheral eosinophilia, and noticeable weight loss. the diagnosis was made on the histologica...

Capillaria hepatica is a very rare zoonotic infestation which primarily infests rodents and is rarely found in humans. The presenting features are fever of unknown origin, hepatomegaly and peripheral eosinophilia. Liver biopsy remains the cornerstone of diagnosis. Treatment of choice is Albendazole and outcome is generally good.

INTRODUCTION Hepatic capillariosis, caused by Capillaria hepatica (Calodium hepaticum) (Bancroft, 1893), Travassos, 1915 (Nematoda, Trichinelloidea, Capillariidae), is a common zoonosis in rodents but is rare in humans. Seventy-two cases in humans have been reported worldwide since the first case was described by MACARTHUR in 192417,27. This study aimed to determine the prevalence of Capillaria...

Multiple exposures to parasitic agents are considered an important factor in the genesis of the most severe forms of the diseases they cause. Capillaria hepatica-induced septal fibrosis of the liver in rats usually runs without signs of portal hypertension or hepatic failure. After determining the hepatic profile of 15 animals during the course of a single infection, we submitted 20 rats to mul...

During an excavation of a site of the corded ware culture in the Saale-Unstrut-Valley (ca. 3000 BC) in Germany, a soil sample from the pelvis of a human skeleton was studied under palaeoparasitological aspects. Eggs of the trematode Fasciola hepatica and of the nematode genus Capillaria were found. This is the first case of a direct association of a F. hepatica-infestation to both a prehistoric...

A 54-year-old male Matsigenka native from the Manu jungle of Peru presented with the eggs shown in Figure 1. Kato Katz (Figure 2) testing revealed 1,500 eggs/g stool. The white blood cell count with differential, liver enzymes, and sputum examination were normal. No treatment was administered; however, repeated stool testing was negative. Pseudocapillariasis caused by Capillaria hepatica was di...

An analytical cross-sectional study of Capillaria hepatica in 307 Norway (brown) rats (Rattus norvegicus) was performed. Rats were trapped in two rural regions in Croatia. The prevalence of adult C. hepatica was 1.95%. The parasite was observed in 6 rats. Of these, 3 out of 189 (1.59%) were male and 3 out of 118 (2.54%) female. The adult parasite was a more common finding in large rats and was ...