this study was carried out to identify the efficacy of caparis spinosa root extract on promastigotes and amastigotes of leishmania major . caparis spinosa extracts were prepared. promastogotes of  l.major (1×10 6 parasites/ml)were incubated at 26 ºc for 24,48 and 72hours in fresh medium(nnn), in absence or presence of different concentrations (0.1,0.3,0.5,0.7,0.9 mg/ml) of caparis spinosa metha...

Caparis spinosa Linn. popularly known as Caper plant is a naturally occurring medicinally important plant of the family Capparaceae. This plant has highly diverse economic and medicinal value in different system of medicine like, Unani, Chinese, Ayurvedicand Arabic. Various parts of C. spinosa are used as drug to treat different diseases especially against hepatic and renal problems. Extract of...

BACKGROUND Pycnocycla spinosa (P. spinosa) a member of the Umbelliferae family is traditionally used for treatment of different ailments. OBJECTIVES This study aimed to evaluate the total phenolic and flavonoid content of P. spinosa extracts (methanol, ethanol and aqueous) and their antioxidant and antimicrobial effects. MATERIALS AND METHODS The antimicrobial activity of different extracts...

Over the past decades, there has been increasing attention on polyphenol-rich foods including fruits and vegetables on human health. Polyphenols have been shown to possess some potential beneficial effects on human health and they are widely found in foods consumed by populations worldwide. Capparis spinosa (C. spinosa) is an important source of different secondary metabolites of interest to hu...

Seed clumps of Capparis spinosa L. together with shoots, leaves and fruits of Cannabis sativa L. were unearthed in the Yanghai Tombs, Turpan District in Xinjiang, China. This is the first time that plant remains of Capparis spinosa have been discovered in China and the eastern part of Central Asia. Based on the joint occurrence of Capparis spinosa and Cannabis sativa, and the pharmacological va...

BACKGROUND/AIM To determine the phenolic acid levels and DNA damage protection potential of Capparis spinosa L. seed extract and to investigate the effect of the extract on cognitive impairment and oxidative stress in an Alzheimer disease mice model. MATERIALS AND METHODS Thirty BALB/c mice divided into 5 groups (control, D-galactose, D-galactose + C. spinosa 50, D-galactose + C. spinosa 100,...

Background and objectives: Capparis spinosa is a perennial herb belonging to the Capparidaceae family that is mainly distributed in arid and semi-arid regions of the tropical and subtropical world. The plant is a potential source of valuable nutrients that is valued for human food. The fruit of this plant, being a rich source of high-value components, is usually pickle...

Pycnocycla spinosa Decne. ex Boiss. var. spinosa (Fam. Umbelliferae) is an essential oil-containing wild plant growing in central part of Iran. Hydroalcoholic extract of Pycnocycla spinosa has antispasmodic and antidiarrheal activity. The aim of this study was to further investigate antidiarrheal and small intestinal transit effect of P. spinosa extract for a comparison with loperamide and dicy...

Bioassay monitoring of hydroalcoholic extract from the aerial part of Pyconcycla spinosa revealed that it contains components with spasmolytic activity in vitro. In addition, P. spinosa extract at oral dose of 1-5 mg/kg inhibits diarrhoea in animal models. Pharmacological screening of pure compounds isolated from P. spinosa hydroalcoholic extract led to the identification of 3,7,10,14,15-pentaa...