نتایج جستجو برای: cannabinoid receptors
تعداد نتایج: 229376 فیلتر نتایج به سال:
Synthetic cannabinoids (SC) are a heterogeneous group of substances with a high affinity for cannabinoid receptors. Unlike Δ9-tetrahydrocannabinol (THC), synthetic cannabinoids are incredibly potent, highly productive, have more affinity for the Cannabinoid receptor type 1 (CB1), and Cannabinoid receptor type 2 (CB2), and are designed to accelerate the effects of tetrahydrocannabinol. Also, the...
conclusions the important role played by endocannabinoid system promises interesting developments, in particular to evaluate the effectiveness of new drugs in both psychiatry and neurology. materials and methods the article is a critical analysis of the most recent data currently present in scientific literature on the subject; a qualitative synthesis of only the most significant articles has b...
results celecoxib reduced the pain behavior in both phases of the formalin test, but this antinociceptive effect was a dose-dependent manner in the late phase. rimonabant alone induced hyperalgesia as compared with the control group and pretreatment of rats with rimonabant reversed the analgesic activity of celecoxib. conclusions antinociceptive effect of celecoxib may be mediated partly throug...
inflammation serves a protective function in controlling infections and promoting tissue repair, and can also cause damage to tissue and disease. many types of cells involved in this process, expressing the components of the cannabinoid signaling system that can be controlled endogenously or pharmacologically. cannabinoids inhibit neuroinflammation and the immune cells express the whole machine...
Background and Objective: It has been shown that cannabinoids exert widespread effects on cognitive functions. An overlapping distribution of GABA with cannabinoid receptors has been reported in some brain structures such as dorsal hippocampus. Thus, the functional interactions between cannabinoid and GABAergic systems in cognitive control seem possible. The present study evaluated the potentia...
introduction: previous studies have shown that the basolateral amygdale (bla) is rich of cb1 cannabinoid receptors and involved in cannabinoid-induced antinociception. also, it seems that there are functional interactions between the cannabinoid cb1 and opioid receptors in the process of sensitization to opiates. in the present study, we tried to examine the role of intra-bla cannabinoid recept...
Background & Aim: Peripheral cannabinoid and glycine receptors are involved in food intake regulation. This study was conducted to investigate the possible interaction between these two receptors in regulating food intake. Methods: This is an experimental study which was conducted on forty male Wistar rats. In the first phase of the experiment, the rats simultaneously received intraperitonea...
Inflammation serves a protective function in controlling infections and promoting tissue repair, and can also cause damage to tissue and disease. Many types of cells involved in this process, expressing the components of the cannabinoid signaling system that can be controlled endogenously or pharmacologically. Cannabinoids inhibit neuroinflammation and the immune cells express the whole machi...
As research has progressed, the cannabinoid CB1 and CB2 receptors have expanded significantly in importance within the neuroscience mainstream. In the presented book leading experts introduce newcomers to the cannabinoid field with chapters covering cannabinoid ligand synthesis and structure activity relationships, the molecular pharmacology of the cannabinoid receptors and the endocannabinoid ...
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