The echinocandins anidulafungin, caspofungin, and micafungin have a broad and similar spectrum of in vitro and in vivo activity against most Candida spp. Minimal inhibitory concentrations (MICs) for Candida spp. are usually below 1 μg/mL for most isolates. The exceptions are Candidaparapsilosis and C. guilliermondii. Species-specific clinical breakpoints (CBPs) and epidemiologic cutoff values (...

The mitochondrial phosphate transport protein (PTP) has been purified in a reconstitutively active form from Saccharomyces cerevisiae and Candidaparapsilosis. ADP/ATP carriers that copurify have been identified. The PTP from S. cerevisiae migrates as a single band (35 kDa) in sodium dodecyl sulfate gels with the same mobility as the N-ethylmaleimide-alkylated beef heart PTP. It does not cross-r...

The present study was conducted to determine the antioxidant and antifungal effects ofmethanol extract from aerial part of Verbascum speciosum. The total phenolic andflavonoid content and the antioxidant activity of the plant extract were determined byusing the Folin-Ciocalteau and the 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radicalscavenging assays. The total phenols and flavonoid content o...

the present study was conducted to determine the antioxidant and antifungal effects ofmethanol extract from aerial part of verbascum speciosum. the total phenolic andflavonoid content and the antioxidant activity of the plant extract were determined byusing the folin-ciocalteau and the 2, 2-diphenyl-1-picrylhydrazyl (dpph) free radicalscavenging assays. the total phenols and flavonoid content o...