cancer patients are more susceptible to adverse drug-drug interactions (ddis) due to receiving multiple medications especially chemotherapy medications, hormonal agents and supportive care drugs. the aim of this study is to describe the prevalence of potential ddis and to identify risk factors for these potential interactions in hospitalized cancer patients in a developing country.a cross-secti...

background and purpose: cancer is associated with significant changes in the lifestyle of patients. spiritual well-being has been shown to be an inherent element of health, quality of life, increased survival rate, and enhanced adaptability of cancer patients with the disease. this study aimed to evaluate the spiritual health of cancer patients and their nurses. methods: this descriptive, corre...

background: cancer diagnosis is an important event in an individual’s life which has considerable outcomes and implications for patient and his/her family. meanwhile, receiving assistance and support from family and friends has a significant impact on patients to help them to cope with disease-related stress and its treatment. this study aimed to assess the received social support and its corre...

background : triple-negative breast cancers (tnbc) are defined as breast cancers with lack of estrogen and progesterone receptors and no overexpression of human epidermal growth factor receptor 2 (her2). this study was performed to determine the frequency and pathologic features of tnbc in iranian patients. subjects and methods: this cross-sectional study was performed on patients with breast c...

background: quantification of radiation-induced apoptosis in peripheral blood lymphocytes (pbls) has been proposed as a possible screening test for cancer-prone individuals and also for the prediction of normal tissue responses after radiotherapy. materials and methods: the neutral version of the comet assay (single-cell gel electrophoresis) was used 24, 48, 72 hours after irradiation with 8 gy...

background: this study was designed to determine the frequency of microsatellite instability (msi) in young iranian pa­tients with endometrial carcinoma and to evaluate its association with histopathologic and clinical features of disease. methods : microsatellite status was analyzed in 23 patients with endometrioid type endometrial cancer who were less than 55 years. clinicopathologic characte...

background: religion, spiritual well-being and hope are concepts that are frequently used as a source of coping in patients with cancer. however, few studies have examined these factors with independent measurement devices. aim: to determine the relationship between religion, spiritual wellbeing, hope and quality of life in cancer patients admitted to omid’s hospital in urmia city from august t...

background: chromosomal alterations play an important role in carcinogenesis. enhanced chromosomal radiosensitivity is shown for many cancer predisposition conditions including breast cancer. in this study chromosomal radiosensitivity and the frequency of background sister chromnatid exchanges (sce) in lymphocytes of normal individuals and breast cancer patients was compared. materials and meth...

cancer patients experience several stressors and emotional upheavals. fear of death, interruption of life plans, changes in body image and self-esteem, changes in social role and lifestyle are all important issues to be faced. moreover, depressive disorders may impact the course of the disease and compliance. the cost and prevalence, the impairment caused and the diagnostic and therapeutic unce...