نتایج جستجو برای: cancer causing genes
تعداد نتایج: 1370181 فیلتر نتایج به سال:
background: an explosion of research has been done in discovering how human health is affected by environmental factors. i will discuss the impacts of environmental cancer causing factors and how they continue to cause multiple disruptions in cellular networking. some risk factors may not cause cancer. other factors initiate consecutive genetic mutations that would eventually alter the normal p...
Background: With approximately 386,000 deaths per year, esophageal cancer is the 6th most common cause of death due to cancer in the world. This cancer, like any other cancer, is the outcome of genetic alterations or environmental factors such as tobacco smoke and gastro-esophageal reflux. Tobacco smoking is a major etiologic factor for esophageal squamous cell carcinoma in western countries, a...
cMaxDriver: A Centrality Maximization Intersection Approach for Prediction of Cancer-Causing Genes in the Transcriptional Regulatory Network
conclusions expression of armc3 in tumor samples and normal adjacent tissue is very important. the expression of this gene in tumor-adjacent tissue may be associated with the stage of cancer; it may be that these tissues are affected by epigenetic and oncogenic changes of breast cancer. accordingly, aberrant expression of armc3 in tumor samples may be an attractive candidate for use as a tumor ...
i n troduction: cancer is a major cause of mortality in the modern world, and one of the most important health problems in societies. during recent years, research on cancer as a system biology disease is focused on molecular differences between cancer cells and healthy cells. most of the proposed methods for classifying cancer using gene expression data act as black boxes and lack biological i...
Background: Cancer and obesity are two major public health concerns. More than 12 million cases of cancer are reported annually. Many reports confirmed obesity as a risk factor for cancer. The molecular relationship between obesity and breast cancer has not been clear yet. The purpose of this study was to investigate priorities of effective genes in the molecular relationship between obesity an...
Cancer is a fatal hereditary illness produced by an unexpected alteration in genes that has the destructive potential to degrade healthy human cells individual. This disease distinguished uncommon molecular promotes unregulated cell proliferation body, which can quickly spread other sites body. Several variables cause cancer humans; these factors might be biological or environmental. Cancer-cau...
The Microarray data consists of various gene expression profiles which are used to identify disease, but the huge dimensions make processing difficult. Assorted techniques like Artificial Bee colony reduce and its effective. level is recognize diseases help in their treatment. By identifying early onset this technique will be able arrest further progress control prognosis, a certain extent, thr...
Background: The molecular studies indicate some of the genes in the promoter region itself, will undergo methylation. Methylation of CpG islands in the promoter region of that cause silence or reduced expression of genes involved in cell growth pathways, which are colorectal cancer causing agents. Detection of methylation status can be used as a marker for cancer diagnosis and prediction of dis...
Gene expression profiling provides insight into the functions of genes at a molecular level. Clustering of gene expression profiles can facilitate the identification of the underlying driving biological program causing genes’ co-expression. Standard clustering methods, grouping genes based on similar expression values, fail to capture weak expression correlations potentially causing genes in th...
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