A mechanism of the transport of nanocrystalline doped calcium carbonatephosphates through the membrane on the model of interaction with phospholipids is considered. Nanocrystalline doped calcium carbonate – phosphates are perspective to transport of the cations in a living cell. Kinetics of the synthesis of nanocrystalline doped calcium carbonatephosphates are non-linear kinetics. Biomaterial b...

The inorganic part of hard tissues (bones and teeth) of mammals consists of calcium phosphate, mainly of apatitic structure. Similarly, most undesired calcifications (i.e. those appearing as a result of various diseases) of mammals also contain calcium phosphate. For example, atherosclerosis results in blood-vessel blockage caused by a solid composite of cholesterol with calcium phosphate. Dent...

Bisphosphonates (BPs) are the most utilized drugs for the treatment of osteoporosis, and are usefully employed also for other pathologies characterized by abnormally high bone resorption, including bone metastases. Due to the great affinity of these drugs for calcium ions, calcium phosphates are ideal delivery systems for local administration of BPs to bone, which is aimed to avoid/limit the un...

Due to the similar chemical properties to the inorganic component in calcified tissues, synthetic calcium phosphate has been considered as ideal biomaterials with excellent biocompatibility. Nanostructured calcium phosphate materials play an important role in the formation of hard tissues in nature. It is reported that calcium phosphates materials in nano-size can mimic the dimensions of consti...

The interest in electrocrystallization of calcium phosphates (CaP) in general, and of hydroxyapatite (HAp) specifically, results from the promising industrial benefits, unique microstructures, and properties of the deposits produced by this process, and the possible similarity to bone mineralization in vivo. In this paper, our work on electrocrystallization of HAp and octacalcium phosphate (OCP...

Solubil ity is one of the most important properties of calcium phosphate salts. It is the solubil ity that determines the direction of many reactions that involve calcium phosphates such as dissolution, precipitation, hydrolysis, and phase transformation. Calcium phosphate solubil ity also plays a maior role in biological processes that involve formation and resorption ol' hard tissues as well ...

Model compounds which resemble the calcium phosphates deposited in biological systems have been synthesised, characterised by a variety of physical techniques and their EXAFS spectra recolded abo~c, the calcium K edge. The spectrum of one of the compounds, hydroxyapatite, has been ;in:~iysecl and the results used to aid the analysis of spectra from related compounds. Spectra recorded above the ...