Almost half of cancer patients experience cachexia syndrome. Cachexic patients are at risk of increased side effects of chemotherapy, reduced tolerance to chemotherapy drugs, longer duration of treatment period, and decreased quality of life. Cancer cachexia is a multifactorial syndrome. Micro ribonucleic acid (miRNA), a “non-coding RNA”, is considered to be a risk factor of cachexia and muscle...

Rationale: Previous studies have shown that serum albumin data from an individual can indicate the onset of cancer cachexia, provide information about a patient's nutritional status, and also serve as biomarker for prognosis patients with cachexia. However, relationship between mortality in cachexia remains unclear.

Background The relationships between cachexia stages and the Functional Assessment of Anorexia/Cachexia Therapy Anorexia Cachexia Subscale (FAACT ACS) 12-item, 5-item anorexia symptoms, 4-item concerns have not been investigated in Asian patients with advanced cancer. Methods This is a multicentre questionnaire survey conducted palliative supportive care settings across Japan. Consecutive were ...

Abstract Introduction Cachexia is a progressively debilitating loss of skeletal muscle often seen in late-stage chronic medical diseases, such as cancer, HIV/AIDS, obstructive pulmonary disease (COPD), and liver cirrhosis. contributes to mortality morbidity with reduced quality-of-life (QoL) treatment options, can be associated adult-onset hypogonadism (AOH), which commonly treated testosterone...

Diabetes mellitus, pathoglycemia, dyslipidemia, non-alcoholic fatty liver, overweight, hypertension, and atherosclerosis are common diseases endangering human health. Cachexia is a life-threatening disease condition. associated with increased mortality. Cancer patients cachexia less tolerant have decreased response to chemotherapy radiation. Do these pathogenesis? We will discuss the commonalit...

BACKGROUND Cachexia is a condition characterized as a loss in body mass or metabolic dysfunction and is associated with several prevalent chronic health conditions including many cancers, COPD, HIV, and kidney disease, with between 10 and 50% of patients with these conditions having cachexia. Currently there is little research into cachexia and our objective is to characterize cachexia patients...

Cancer Cachexia afflicts 50 - 80 percent of cancer patients with roughly 20 all dying cachexia. Metabolomics is the study different metabolites, their location in body, and timing appearance disappearance. As a result, this science can be applied to solve problem Cachexia. In review, I examine recent studies on metabolism that use as instrument discovery. Further, review details potential thera...

PURPOSE OF REVIEW Cachexia is a common negative consequence of cancer and is often unrecognized. To assess cachexia, malnutrition assessment tools are used. This review discusses the advantages and disadvantages of the current malnutrition assessment tools and describes the requirements for a comprehensive cachexia assessment instrument and its implication for clinics and research. RECENT FIN...

BACKGROUND Cachexia is a multifactorial syndrome that is highly prevalent in advanced cancer patients and leads to progressive functional impairments. The classification of cachexia stages is essential for diagnosing and treating cachexia. However, there is a lack of simple tools with good discrimination for classifying cachexia stages. Therefore, our study aimed to develop a clinically applica...

Despite the development of consensus-based frameworks to define cancer cachexia, the validity and usefulness of these frameworks are relatively unknown. The aim of the present study was to study the presence of pre-cachexia and cachexia in patients with stage III nonsmall-cell lung carcinoma (NSCLC) by using a cancer-specific framework and a general framework for cachexia, and to explore the pr...