Background The normal cells derived from human embryonic stem cells (hESCs) are regarded as substitutes for damaged or dysfunctional adult cells. However, tumorigenicity of hESCs remains a major challenge in clinical application of hESC-derived cell transplantation. Previously, we generated monoclonal antibody (MAb) 57-C11 specific to the surface molecule on undifferentiated hESCs. The aim of t...

The Chinese hamster cell line EM-C11 has been shown to be 5 times more sensitive than its parental line CHO9, but not hypermutable, after treatment with ethyl methanesulfonate. Ethyl methanesulfonate-induced mutational spectra were determined at the hprt locus to investigate whether the same adducts are responsible for mutation induction in both cell lines. The mutational spectra for EM-C11 and...

Alkylated silicon nanocrystals (C11-SiNCs) were prepared successfully by galvanostatic etching of p-Si(100) wafers followed by a thermal hydrosilation reaction of 1-undecene in refluxing toluene in order to extract C11-SiNCs from porous silicon. Erbium trichloride was added to alkylated SiNCs using a simple mixing chemical route. To the best of our knowledge, this is the first investigation on ...

Type XI collagen has been associated with tumor fibrosis and aggressiveness in patients pancreatic ductal adenocarcinoma (PDAC). The propeptide on is released into the circulation after proteolytic processing at either amino acid 253 or 511. This allows for a noninvasive biomarker approach to quantify production. We developed two ELISA-based biomarkers, targeting enzymatic cleavage sites (PRO-C...

Despite the conceptual simplicity of sequential consistency (SC), the semantics of SC atomic operations and fences in the C11 and OpenCL memory models is subtle, leading to convoluted prose descriptions that translate to complex axiomatic formalisations. We conduct an overhaul of SC atomics in C11, reducing the associated axioms in both number and complexity. A consequence of our simplification...

Two bacterial strains designated C9 and C11 were isolated and characterized from black tiger shrimp Penaeus monodon maintained in laboratory conditions. The shrimp exhibited tiny white spots along with clinical signs of bacterial infection, probably, due to suboptimal water quality and resulting stress. Absence of white spot syndrome virus was confirmed by PCR. Bacterial isolates obtained from ...

RNA polymerase III recognizes and pauses at its terminator, an oligo(dT) tract in non-template DNA, terminates 3' oligo(rU) synthesis within this sequence, and releases the RNA. The pol III subunit Rpc11p (C11) mediates RNA 3'-5' cleavage in the catalytic center of pol III during pausing. The amino and carboxyl regions of C11 are homologous to domains of the pol II subunit Rpb9p, and the pol II...

Verification techniques for C11 programs have advanced significantly in recent years with the development of operational semantics and associated logics increasingly large fragments C11. However, these been developed a restricted setting to avoid thin-air-read problem. In this article, we propose an that leverages intra-thread partial order (called semantic dependencies ) induced by recently de...