introduction: otorrhea and granulation tissue in canal wall down mastoidectomy (cwd) is the common problem in cholesteatoma removal and leads to many discomfort for both the patient and the physician. the main objective in cwd is creating the dry cavity, so the topical antibiotic and acetic acid in variable saturations are used for this purpose. in this study we evaluate the effectiveness of to...

lentinan a polysaccharide from medicinal mushroom i.e lentinus, has been known to have anticancer properties. telomerase activity is not observed in normal healthy cells, whereas in cancerous cells telomerase expression is high. telomerase represents a promising cancer therapeutic target. we investigated the inhibitory effect of lentinan on telomerase reverse transcriptase gene (htert) which is...

Background: Despite demonstration of molecular and biochemical changes induced by heat shock on Leishmania, the immunological importance of such changes has not been elucidated.  Objective: Studying the effect of two excretory factors prepared under heat shock and ambient temperature from Leishmania major on Balb/c splenocytes function.  Methods: The parasites were cultured at 25°C and then sub...