background and objectives: nowadays corn flakes are the most common form of breakfast cereals however, their vitamins are declined during the baking process. in this research, production of fortified corn flakes by lactobacillus plantarum and l. reuteri, as well as incorporation of oat and malt fiber as prebiotics have been studied. materials and methods: plackett-burman statistical design was ...

this paper describes optimization method that combines the plackett-burman design, a factorial design and the response surface method, which were used to optimize the medium for the production of l-asparaginase by serratia marcescens sb08. four medium factors, from out of 11 medium factors, were screened by plackett-burman design experiments and subsequent optimization process to find out the o...

Antioxidants are molecules that scavenge or neutralize free radicals. Free radicals are generated in human body during normal physiological processes and have implications on various human diseases. Endophytic fungi from medicinal plants are gaining tremendous impetus as potential source of antioxidant compounds. In this studyPlackett-Burman design was used to evaluate the media components affe...

plackett-burman design was used for selection of important media components such as carbon and nitrogen sources and minerals which affect poly(hydroxybutyrate) production and cell growth of methylobacterium extorquens dsmz 1340. among the studied variables, nitrogen and phosphorus sources, mgso4 and most of the trace elements were found to be significant variables for phb production from methan...

This paper describes optimization method that combines the Plackett-Burman design, a factorial design and the response surface method, which were used to optimize the medium for the production of L-asparaginase by Serratia marcescens SB08. Four medium factors, from out of 11 medium factors, were screened by Plackett-Burman design experiments and subsequent optimization process to find out the o...

a solid state fermentation method was used to utilize wheat straw as substrates for citric acid production by using aspergillus niger atcc 9142. the plackett burman design (pbd) of experiments was used to test the relative importance of the variables affecting production such as moisture content, age of spore, inoculum size, initial ph of substrate, methanol concentration, incubation temperatur...

Plackett-Burman experimental design was used to screen important medium components influencing the production of polyribosyl ribitol phosphate by Haemophilus influenzae type-B under submerged fermentation. Eleven media parameters such as Glutamic acid, Yeast extract, cystein, dextrose, NAD, heamin, NaCl, NH4Cl, Na2HPO4, KCl, and MgSO4.7H2O were screened in twelve experimental runs as per the de...

background: hydrocarbons degradation is principally achieved by microorganisms in natural environments. the extent of hydrocarbons biodegradation is mainly conditioned by environmental factors and its success depends on the optimal condition for the crude oil degrading isolates. objectives: the aims of the current study was to isolate and identify crude oil degrading bacterium from surface sedi...

The objective of this work was design, characterization, and optimization of controlled drug delivery system containing antibiotic drug/s. Osmotic drug delivery system was chosen as controlled drug delivery system. The porous osmotic pump tablets were designed using Plackett-Burman and Box-Behnken factorial design to find out the best formulation. For screening of three categories of polymers, ...