background: anecdotal information has suggested that sodium benzoate is used with more than permissible doses during production steps of food products especially pickles and pickled cucumbers in food producing factories in markazi province and other food producing factories . the present study was done to evaluate factual concentration of sodium benzoate in these products. methods: in this stud...

Background: Anecdotal information has suggested that sodium benzoate is used with more than permissible doses during production steps of food products especially pickles and pickled cucumbers in food producing factories in Markazi province and other food producing factories . The present study was done to evaluate factual concentration of sodium benzoate in these products. Methods: In this ...

The accurate formation of synaptic vesicles (SVs) and incorporation of their protein cargo during endocytosis is critical for the maintenance of neurotransmission. During intense neuronal activity, a transient and acute accumulation of SV cargo occurs at the plasma membrane. Activity-dependent bulk endocytosis (ADBE) is the dominant SV endocytosis mode under these conditions; however, it is cur...

Ship unloader grabs are usually designed using the manufacturer’s in-house knowledge based on a traditional physical prototyping approach. The grab performance depends greatly properties of bulk material being handled. By considering cargo variability in design process, can be improved significantly. A multi-objective simulation-based optimization framework is therefore established to include p...

The targeting of proteins and lipids to the cell surface domains of polarized cells is not a simple bulk flow process but requires sorting into distinct apical and basolateral pathways from the trans-Golgi network. Here, we describe the sorting determinants in the cargo molecules, the cellular sorting machineries responsible for the hierarchical read-out of the signals, and the mechanisms of ca...

Economic growth has a direct link with the volume of cargo at port terminals. To encourage growth, investment decisions on infrastructure are required that can be performed by development econometric models. We compare three time-series models and one machine-learning model to estimate forecast volume. apply an ARIMA+GARCH+Bootstrap, multiplicative Holt-Winters, support vector regression model,...

The shippers have the requests for the accessibility and economics of logistics on the premise of cargo safety, and the cargo shipping safety is an important part of logistics safety. Thus, it is quite essential to monitor the cargo shipping safety. The data is difficult to obtain in the research for cargo shipping safety, thus it cannot cover all states of influencing factors during modeling p...

Many plasma membrane (PM) proteins enter cells nonselectively through clathrin-independent endocytosis (CIE). Here, we present evidence that cytoplasmic sequences in three CIE cargo proteins-CD44, CD98, and CD147-were responsible for the rapid sorting of these proteins into endosomal tubules away from endosomes associated with early endosomal antigen 1 (EEA1). We found that Hook1, a microtubule...