background: this study aimed to assess the effectiveness of topiramate, a glutamate-modulating agent, in patients with treatment-resistant obsessive-compulsive disorder (ocd) as an adjunct to serotonin reuptake inhibitors (sris). materials and methods: thirty-eight patients with refractory ocd, were randomly assigned to receive topiramate or placebo. this study was designed as a 12-week, double...

BACKGROUND Obsessive-compulsive disorder typically begins early in life and has a chronic course. Despite the need for long-term treatment, the information about therapeutic effect on different clinical subtypes is limited. METHODS Consecutive outpatients with obsessive-compulsive disorder were evaluated for response to a two-month fluoxetine therapy course by Yale-Brown obsessive-compulsive ...

OBJECTIVE The primary objective of this study was to examine neurological soft signs in patients with obsessive-compulsive disorder compared with patients with schizophrenia and a control group in the Indian setting. The secondary objective was to find any correlation between age at onset and neurological soft signs scores, as well as that between severity of obsessive-compulsive disorder sympt...

OBJECTIVE Recent factor-analytic studies of obsessive-compulsive disorder identified consistent symptom dimensions. This study was designed in order to observe which obsessive compulsive symptom dimensions could be changed by adding two individual sessions of motivational interviewing and thought mapping of cognitive-behavioral group therapy using a randomized clinical trial. METHOD Forty out...

There are many comorbid disorders associated with autism spectrum disorders in child and adolescent population. Although obsessive compulsive disorder and autism spectrum disorders (ASD) comorbidity has common in clinical practice, there are few reports about psychopharmacological treatment for obsessive compulsive symptoms in children with ASD in the literacy. We report a successful treatment ...

BACKGROUND Blepharospasm (BS) is a form of central focal dystonia recently associated with psychiatric disorders, particularly obsessive and compulsive symptoms. Hemifacial spasm (HFS) represents a focal myoclonus with peripheral origin in the facial nerve. OBJECTIVE To determine the frequency of obsessive and compulsive symptoms in patients with BS in comparison with patients with HFS. MET...

Objective: This study investigates obsessive-compulsive disorder patients in terms of strategic planning and its association with specific obsessivecompulsive symptom dimensions. Method: We evaluated 32 obsessivecompulsive disorder patients. Strategic planning was assessed by the ReyOsterrieth Complex Figure Test, and the obsessive-compulsive dimensions were assessed by the Dimensional Yale-Bro...

OBJECTIVES To compare the effectiveness of cognitive behaviour therapy delivered by telephone with the same therapy given face to face in the treatment of obsessive compulsive disorder. DESIGN Randomised controlled non-inferiority trial. SETTING Two psychology outpatient departments in the United Kingdom. PARTICIPANTS 72 patients with obsessive compulsive disorder. INTERVENTION 10 weekl...

PURPOSE The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) is regarded as the most acceptable tool for measuring obsessive-compulsive disorder symptom severity. Recently, the Yale-Brown Obsessive Compulsive Scale - Second Edition (Y-BOCS-II) was developed for better measurement. The study reported here aimed to evaluate the psychometric properties of the Thai version of the Yale-Brown Obsessive...

the aim of the present study is to investigate the relationship between obsessive-compulsive symptoms (ocss) and negative and positive symptoms in schizophrenia.subjects of the study comprised of 31 schizophrenia with obsessive-compulsive symptoms (19 men and 12 women) selected by convenience sampling method from iran psychiatric hospital. the diagnoses were established on the basis of dsm-iv-t...