Three rapid spectrophotometric methods were developed for the determination of sunitinib based on the formation of ion-pair complex in acidic medium with bromocresol purple, bromothymol blue, and bromophenol blue. The formed ion-pair complexes, extractable with chloroform, were measured at 422 nm for bromocresol purple, 425 nm for bromothymol blue and 427 nm for bromophenol blue. All these meth...

Three rapid spectrophotometric methods were developed for the determination of sunitinib based on the formation of ion-pair complex in acidic medium with bromocresol purple, bromothymol blue, and bromophenol blue. The formed ion-pair complexes, extractable with chloroform, were measured at 422 nm for bromocresol purple, 425 nm for bromothymol blue and 427 nm for bromophenol blue. All these meth...

a simple extractive spectrophotometric method has been developed for the estimation of miconazole nitratein both pure and pharmaceutical preparation. the method is based on the formation of ion-pair complex of thedrug with acidic dye bromothymol blue (btb) in acidic condition, followed by its extraction in organic solvent(chloroform). the absorbance was measured against the corresponding blank....

A new plating medium using bromothymol blue (BTB) indicator is described and compared with eosin-methylene blue (EMB), MacConkey, and Endo media. These media were tested with L-arabinose by plating fermenting and nonfermenting mutant strains of Escherichia coli. The minimum concentrations of L-arabinose that permitted differentiation of these strains were determined. Different concentrations we...

This paper, the second in a series concerning the use of indicator dyes to study the reactions of organic acids and bases in organic solvents, deals with halogen derivatives of phenolsulfonephthalein. Spectrophotometric data are given for mixtures of bromocresol green, bromophenol blue, iodophenol blue, and tetrabromophenol blue with primary, secondary, and tertiary aliphatic amines in benzene;...

Four simple and sensitive visible spectrophotometric methods have been developed for the assay of dutasteride. Method I describes the interaction of dutasteride, as an n-electron donor, with chloranil, as a pi-acceptor, in acetonitrile to give reddish orange colored chloranil radical anion with absorption maxima at 525 nm. Method II involves the oxidative coupling reaction of dutasteride with 3...

1. The renal excretion of phenol red and other phenolsulphophthalein dyes (bromophenol blue and bromothymol blue) was studied in clearance experiments on anaesthetized rabbits. 2. Net tubular excretion of phenol red reached a maximal value of 8 mumole/min at a plasma concentration of ultrafiltrable dye of about 0.1 mM and was decreased at higher plasma concentrations. Decreases in net tubular e...