نتایج جستجو برای: bridged bithiazoles

تعداد نتایج: 7288  

Journal: :iranian journal of chemistry and chemical engineering (ijcce) 2000
reza mostaghim

bridged bithiazoles (5,5'-ethylene-4,4'-bithiazoles) are synthesized as a good chelating agent.

Reza Mostaghim

Bridged bithiazoles (5,5'-ethylene-4,4'-bithiazoles) are synthesized as a good chelating agent.

2014
Keith C. Coffman Huy H. Nguyen Puay-Wah Phuan Brandi M. Hudson Gui J. Yu Alex L. Bagdasarian Deanna Montgomery Michael W. Lodewyk Baoxue Yang Choong L. Yoo A. S. Verkman Dean J. Tantillo Mark J. Kurth

Conformationally constrained bithiazoles were previously found to have improved efficacy over nonconstrained bithiazoles for correction of defective cellular processing of the ΔF508 mutant cystic fibrosis transmembrane conductance regulator (CFTR) protein. In this study, two sets of constrained bithiazoles were designed, synthesized, and tested in vitro using ΔF508-CFTR expressing epithelial ce...

2007
Hideaki

plexes of amines and cyclic amines used as DNA cleavage agents have been reported. These compounds generally contain heterocycles or polycyclic aromatic rings tethered to one or more aminoalkyl side chains, and are complexed with transition metals known to play important roles in DNA cleavage reactions. Many studies on the role of 2,4 -bithiazole, which constitutes a part of the C-terminus of B...

2013
Tip W. Loo M. Claire Bartlett David M. Clarke

Better correctors are needed to repair cystic fibrosis transmembrane conductance regulator (CFTR) processing mutants that cause cystic fibrosis. Determining where the correctors bind to CFTR would aid in the development of new correctors. A recent study reported that the second nucleotide-binding domain (NBD2) was involved in binding of bithiazole correctors. Here, we show that bithiazole corre...

F. Mollaamin K. Zare M. Sayadian

An azobenzene bridge was introduced into the lower (or smaller) rim of p-tert-butylcalix[8]arene to form 1,5-singly bridged calix[8]arene derivatives, respectively. Bridged calix[8]arene of conformationally rigid wereisolated. The stability of the two structures of bridged calix[8]arenes have been compared.The study of organicstructure to form nanoporous structures is a well known in chemistry ...

Journal: :journal of physical & theoretical chemistry 2011
m. sayadian k. zare f. mollaamin

an azobenzene bridge was introduced into the lower (or smaller) rim of p-tert-butylcalix[8]arene to form 1,5-singly bridged calix[8]arene derivatives, respectively. bridged calix[8]arene of conformationally rigid wereisolated. the stability of the two structures of bridged calix[8]arenes have been compared.the study of organicstructure to form nanoporous structures is a well known in chemistry ...

Journal: :iranian journal of chemistry and chemical engineering (ijcce) 1998
saeid amani javad zolgharnein leeroy j. theriot

tow new compound of type [(chelate)2cu-oh-cu(chelate)2] x3.nh2o, where chelate=1,10-phenanthroline; x=cl¯(n=3.5) and chelate=4,4'-dimethyl-2,2'-bipyridine;  (n=5) have been synthesized and their properties investigated. the complexes show room temperature magnetic moment order of 1.0 b.m. per copper atom. the x-band esr spectrum of powdered samples at room temperature shows typical dm=1 transit...

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