background: invasive ductal carcinoma is the most common type of breast cancer in iran. impaired immune responses occur frequently in cancer patients, but the mechanisms of the induced immune defects remain poorly understood. it is believed that infiltrated immune cells, especially macrophages, may provide help for tumor cell growth and metastasis.   objective: to analyze the status of tumor as...

recent studies have indicated the profound  anti-tumor activity of artemisinin's compounds,  among  which;  arteether  is an  oil-soluble derivative of  artemisinin with an endoperoxide bridge that can induce apoptosis in tumor cells but not in the normal cells. an experiment was carried out on tumor-bearing balb/c mice to estimate the effects of arteether  on  tumor  growth  and  antitumor  im...

background: alteration in peripheral blood lymphocytes (pbls) is usually investigated to provide an evidence of the host immune responses to tumor antigens. the tumor infiltrating nk cells interact most closely with the tumor cells and more accurately reflect tumor host interactions. objective: to analyze peripheral blood and tumor associated natural killer (nk) cells in patients with breast ca...

background: studies have shown that obese individuals are at increased risk of breast cancer development and poorer prognosis. leptin, an adipose tissue-derived hormone, has pro-inflammatory and proliferative effects and a well-established association with several comorbidities of obesity. this study was designed and conducted to compare the serum levels of leptin in patients with malignant and...

desmoid tumor of breast is a rare benign, locally aggressive tumor with a high recurrence rate. it has been associated with scar from previous breast surgery or trauma. especially in breast cancer patients with previous operation history, it may simulate recurrent breast cancer clinically and radiologically. we presented multimodality imaging findings (ultrasound, computed tomography, magnetic ...

background: cardiac risk assessment with myocardial perfusion imaging (mpi) is a common practice for some elderly breast cancer patients who are candidates for operation. in rare cases the tumor may become visible in the images. case presentation: this is the report of a case with a huge slow-growing breast tumor suspicious for malignancy and presenting with methoxy-isobutyl-isonitrile (mibi) u...

circulating tumor cells (ctcs) recognition and characterization in the peripheral blood of patients with breast cancer have proven practical and predictive value in different studies. however, the clinical significance of ctcs enumeration and molecular characterization in thepersonalization of breast cancer diagnosis and treatment remains under the debate. a literature search in pubmed, web of ...

colorectal cancer most commonly metastasizes to the liver and lung. metastatic colon carcinoma (mcc) to the breast is extremely rare. krukenberg tumor is an uncommon metastatic tumor of the ovary. case presentation: a 38 years woman presented with abdominal pain. in evaluation colon cancer was diagnosed at stage 3. folfox chemotherapy was done. after one year she developed krukenberg tumor. few...

breast cancer is a malignant tumor and the most common cancer among american women that starts from cells of the breast. the growth of the size of data exceeds the ability of humans to analyze the data. so we need some intelligent machines that can analyze datasets intelligently for us. we propose a multi nominal logit model to evaluate correlation between risk factors of breast tumor. our mode...

background: our study aims to determine the correlation between breast cancer tumor size according to imaging (ultrasonography and mammography) with final pathologic report as a gold standard. methods: we included 132 women with pathologically proven invasive breast cancer between april 2011 and december 2013. study variables included tumor size according to pathology (as a gold standard), ultr...