نتایج جستجو برای: brain stem injury

تعداد نتایج: 963168  

Journal: :مجله علوم اعصاب شفای خاتم 0
maryam borhani-haghighi a. shefa neuroscience research center, khatam alanbia hospital, tehran, iran b. department of anatomy, tehran university of medical sciences, tehran, iran fatemeh alipour shefa neuroscience research center, khatam alanbia hospital, tehran, iran

naturally the brain is ineffective in regenerating functional tissue after disease or injury, so to overcome these defects innovative curative strategies such as stem cell transplantation and tissue engineering have to be considered. researchers investigate the use of strategies to attain better functional repair results. one of the important challenges of effective transplantation is the deliv...

Journal: :مجله علوم اعصاب شفای خاتم 0
nasibeh ghandy neuroscience department, mashhad university of medical sciences, mashhad, iran sajad sahab negah neuroscience department, mashhad university of medical sciences, mashhad, iran

traumatic brain injury (tbi) is defined as an external mechanical injury to the brain. neuroinflammation plays a vital role in the pathophysiology of tbi. microglia and astrocytes play a central role in the initiation and regulation of inflammation. numerous pro-inflammatory mediators including cytokines, chemokines, reactive oxygen species (ros) and nitric oxide (no) released by microglia. in ...

Journal: :مجله علوم اعصاب شفای خاتم 0
sajad sahab negah a. department of neuroscience, mashhad university of medical sciences, mashhad, iran b. shefa neuroscience research center, khatam alanbia hospital, tehran, iran

the incidence of traumatic brain injury (tbi) are annually increasing, developed tissue engineering methods could represent the definite remedies for patients with strongly injured central nervous system and have a great effect in the public healthcare cost. the current clinical treatments in tbi display several limitations. furthermore, several therapies, coming from neural tissue engineering ...

Journal: :مجله علوم اعصاب شفای خاتم 0
pardis oliazadeh faculty of medicine, mashhad university of medical sciences, mashhad, iran hasan abbasian neuroscience department, faculty of medicine, mashhad university of medical sciences, mashhad, iran moniba bijari faculty of medicine, mashhad university of medical sciences, mashhad, iran fateme gholami zohan neuroscience department, faculty of medicine, mashhad university of medical sciences, mashhad, iran sajad sahab negah a. neuroscience department, faculty of medicine, mashhad university of medical sciences, mashhad, iran b. shefa neuroscience research center, khatam alanbia hospital, tehran, iran

introduction: brain injury is an important cause of morbidity and mortality worldwide and so far, there has been no absolute treatment for the damaged brain tissue. using human stem cells with self-assembling scaffolds can be a promising method for treatment of traumatic brain injury. materials and methods: human meningioma stem cells were isolated, cultured and then expanded into in vitro cond...

Fateme Gholami Zohan, Hasan Abbasian, Moniba Bijari, Pardis Oliazadeh, Sajad Sahab Negah,

Introduction: Brain injury is an important cause of morbidity and mortality worldwide and so far, there has been no absolute treatment for the damaged brain tissue. Using human stem cells with self-assembling scaffolds can be a promising method for treatment of traumatic brain injury. Materials and Methods: Human meningioma stem cells were isolated, cultured and then expanded into in vitro cond...

Journal: :acta medica iranica 0
bahram samadi rad department of iranian legal medicine organization, tabriz, iran. ali zeinali department of neurosurgery, imam khomeini hospital, school of medicine, tabriz university of medical sciences, tabriz, iran. moslem shakeri bavil department of neurosurgery, imam khomeini hospital, school of medicine, tabriz university of medical sciences, tabriz, iran. fereydun ashrafian general practioner, east azerbaijan legal medicine center, tabriz, iran. mohammad ali daghighi department of neurosurgery, imam khomeini hospital, school of medicine, tabriz university of medical sciences, tabriz, iran.

computed tomography (ct) is now the primary diagnostic method for head trauma because of its ability to demonstrate the nature, extent, sites, and multiplicity of brain injuries. although there have been numerous reports on the ct findings of most types of intracranial injury, the findings in brainstem injury have not been well described. this study aimed at comparing the autopsy findings of br...

Ali Gorji, Ali Jahanbazi Jahan Abad, Arezou Es'haghabadi, Fatemeh Gholami, Pardis Oliazadeh, Sajad Sahab Negah, Sedigheh Ghasemi,

Traumatic brain injury is considered as one of the main causes of morbidity and mortality worldwide. Apart from primary mechanical injury, Secondary injuries due to inflammation and apoptosis result in great neuronal damage. Current treatments are not able to regenerate the damaged part and prevent future sequels. Using human stem cells with self-assembling scaffolds may be promising in treatme...

Journal: :مجله علوم اعصاب شفای خاتم 0
sajad sahab negah a. department of neuroscience, mashhad university of medical sciences, mashhad, iran b. shefa neuroscience research center, khatam alanbia hospital, tehran, iran ali jahanbazi jahan-abad a. shefa neuroscience research center, khatam alanbia hospital, tehran, iran b. department of clinical biochemistry, shahid beheshti university of medical sciences, tehran, iran ali gorji a. department of neuroscience, mashhad university of medical sciences, mashhad, iran b. shefa neuroscience research center, khatam alanbia hospital, tehran, iran c. epilepsy research center, department of neurology, and department of neurosurgery, westfälische wilhelms-universität münster, münster, germany

traumatic brain injury (tbi) is described by a disruption in the normal function of the brain due to an injury following a trauma, which can potentially cause severe physical, cognitive, and emotional impairment. the use of human stem cells and self-assembling peptide scaffolds suggest huge potential for application in the treatment of tbi. in the present study, we surveyed the beneficial effec...

Ali Gorji, Ali Jahanbazi Jahan-Abad, Hassan Hosseini Ravandi, Maryam Khaleghi Ghadiri, Sajad Sahab Negah, Sedigheh Ghasemi, Walter Stummer,

Traumatic brain injury (TBI) is a disruption in the brain functions following a head trauma. Cell therapy may provide a promising treatment for TBI. Human neural stem cells cultured in self-assembling peptide scaffolds have been proposed as a potential novel method for cell replacement treatment after TBI. In the present study, we accessed the effects of human neural stem/progenitor cells (hNS/...

Journal: :مجله علوم اعصاب شفای خاتم 0
sajad sahab negah a. shefa neuroscience research center, khatam alanbia hospital, tehran, iran b. histology and embryology group, basic science department, faculty of veterinary medicine, shiraz university, shiraz, iran zabihollah khaksar histology and embryology group, basic science department, faculty of veterinary medicine, shiraz university, shiraz, iran elham mohammad zadeh shefa neuroscience research center, khatam alanbia hospital, tehran, iran mostafa modarres mousavi shefa neuroscience research center, khatam alanbia hospital, tehran, iran ali jahanbazi jahan-abad shefa neuroscience research center, khatam alanbia hospital, tehran, iran

a common pathological process that occurred after brain injury is gliosis. gliosis involves the activation of glial cells to proliferate and become hypertrophic to occupy the injured brain areas. in order to form a defense system against the invasion of micro-organisms and cytotoxins into surrounding tissue, glial cells including astrocytes and microglia undergo reactive response to injury. neu...

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