formula one legend michael schumacher hit his head severely while skiing on december 29, 2013. he was operated on for brain decompression and left in a coma fighting for life. in such severe brain injury with cerebral contusion and hemorrhage following head trauma, refractory to medical therapy and with increasing cerebral oedema and intracranial pressure, critically low cerebral perfusion can ...

objectives the aim of this study was to present the incidence and characteristics of repeated tbi (rtbi) in iranian patients. patients and methods during one year, all admitted tbi patients with prior tbi history were enrolled into the study. in each patient, data such as age, gender, past medical history, injury cause, anatomic site of injury, tbi severity, clinical findings and ct scan findin...

background traumatic brain injury (tbi) is a worldwide problem, especially in countries with high incidences of road traffic accidents such as iran. patients with a single occurrence of tbi have been shown to be at increased risk to future tbi. this study presents incidences and characteristics of repeated traumatic brain injury (rtbi) in iran. materials and methods during one year, all admitte...

traumatic brain injury (tbi) is one the most common cause of disability between young adults. these people have been socially isolated during post-surgery traumatic brain injury. in this study we investigated the effect of social isolation on the structural deficits after tbi in the young rats. young rats were divided into control group with social interaction, sham group with social isolation ...

there are only a few, non-evidence based, neuroprotective strategies for treatment and prevention of brain injuries after closed head trauma. to establish new therapy strategies, a novel animal model is needed. the aim of our investigation was to link standardized small animal models and actual patient medical care. data of experimental small animal studies often cannot be transferred to cns in...

traumatic brain injury (tbi) is an important clinical problem in the worldwide and especially due to breaking driving rules in iran, but undesirable consequences of trauma can persist for the rest of patient’s life. we investigated the effect of a novel weight drop model of tbi on incidence of seizure 2 weeks after tbi. in this regard, 21 male wistar rat weighted 250-300 gr randomly were divide...

patients and methods the study was performed on 40 tbi patients referred to the shahid beheshti hospital of kashan city and 40 normal controls in kashan. traumatic brain injured patients and normal controls were selected by convenience sampling. two groups filled out the demographic sheet, cognitive failures questionnaire (cfq) and meta-cognitions questionnaire 30 (mcq-30). the data were analyz...

in the mammalian, there are three ncx genes (ncx1, ncx2, ncx3), which their three proteins are differentially expressed in distinct regions of the central nervous system, where they might underlie different physiological and pathophysiological functions. ncx is a nine-transmembrane protein which is distributed in the brain widely. ncx operates in a bidirectional way, and exchanges ca2+ and na+ ...

conclusions increased serum levels of interleukins 6 and 8 as a predictive marker might be associated with unfavorable clinical outcome in patients with severe tbi. results comparing the serum levels of interleukins in two groups with favorable and unfavorable clinical outcomes showed that the mean serum levels of interleukins 6 and 8 in group with favorable outcome was 85.2 ± 51.6 and 52.2 ± 3...

objective: to describe the epidemiological and clinical characteristics of fall injuries in east azerbaijan, iran. methods: this cross-sectional study was based on hospital information system (his) data for patients referred to the imam reza hospital between 2008 and 2013. we recorded the demographic characteristics and epidemiological patterns of patients who were admitted to our center due to...